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MetaSystem Metafer - User Manual

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Quick Guide
Metafer
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MetaSystems Hard & Software GmbH
(MetaSystems)
Robert-Bosch-Str. 6
68804 Altlussheim
Germany
Tel: +49 (0)6205 39610
Fax: +49 (0)6205 32270
Email: info@metasystems.de
Document Number :
H-1200-004-SA Rev. 1 (2021-09)
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Summary

About this Quick Guide

Assumptions on Previous Knowledge

Assumes basic computer literacy and knowledge of laboratory techniques for image interpretation.

How to Obtain More Information

Guide provides introduction; comprehensive details in built-in help files and manuals.

Compliance Notice

Electrical Safety Compliance

Details compliance with directives for electrical equipment safety within voltage limits.

Electromagnetic Compatibility (EMC)

Outlines compliance with directives for electromagnetic compatibility for equipment.

Instrumentation Identification Marking

Specifies CE mark and its meaning for IVD products.

Symbols Used

CE and IVD Symbol Meanings

Explains CE mark compliance and IVD usage for diagnostic devices.

General Warning Symbols

Details symbols for Manufacturer, Caution, and Consult Instructions for use.

Safety Instructions

General Provisions

Covers intended use, operator responsibilities, and system requirements for laboratory use.

Specific Provisions

Laboratory Safety Guidelines

Advises consulting laboratory safety guidelines and regulations for equipment use.

Qualified Personnel Operation

Stipulates system operation by qualified and trained laboratory personnel only.

Electrical Shock Hazard

Warns about risk of electric shock from improper grounding of electrical outlets.

Motorized Focus Drive Hazards

Alerts to personal injury and system damage risks with motorized focus drives.

Gas Discharge Lamp Hazards

Warns about explosion and radiation risks from gas discharge lamps used in fluorescence.

Notes on Warranty

Setup and Operation

Ambient Conditions and Site Selection

Recommends stable ambient temperatures and appropriate installation sites for operation.

Fluorescence Preparation Guidelines

Advises against exposing fluorescence preparations to direct sunlight to minimize stray light.

Staining and FISH Considerations

Notes software capabilities for enhancement but not correction of staining/FISH imperfections.

Setup and Operation - Environmental and System Details

Vibration Avoidance

Recommends installation location with minimum vibration for experimental procedures.

Minimal Space Requirements

Specifies minimum area requirements for system setup and applicable regulations.

Power Supply Recommendations

Suggests UPS usage for voltage fluctuations, warns against connecting laser printers to UPS.

Computer Network Configuration

Details network requirements for connecting multiple systems using Cat. 5 cables.

System Settings Modification

Advises against changing system settings without MetaSystems personnel or experienced users.

Dust and Dirt Protection

Emphasizes protecting the microscope and camera from dust to maintain functionality.

Cleaning Procedures

Provides guidelines for safe cleaning of equipment using a soft damp cloth.

Sensitive Fluorescence Filters

Highlights sensitivity of fluorescence filters to heat and potential irreversible damage.

Software Updates

Informs about availability of free software updates for one year after installation.

Camera Warming Effects

Explains camera warming and its impact on signal-to-noise ratio, suggesting heat dissipation.

Product Descriptions

System Components Overview

Products consist of software modules, hardware components, and accessories in various configurations.

Neon - Intended Use

Neon is MetaSystems' platform for case and image data organization for all devices.

Neon - Legal Classification

Details legal classification of MetaSystems products as IVD devices in different regions.

Product Variants

Neon Client License Variants

Describes two Neon product variants for client licenses and combination options.

Metafer - Intended Use

Metafer is for acquisition of microscopic images using automated slide scanning.

Metafer - Legal Classification

Provides legal classification for Metafer and Relosys modules in various countries.

Product Variants - Metafer Modules

Automated Metaphase Finder (MSearch)

Describes MSearch for searching and relocating metaphases on slides.

Automated Scanning System (MetaCyte)

Details MetaCyte system for analysis of cells and cellular parameters.

Automated Scanning System (RCDetect)

Describes RCDetect for detection and relocation of rare cells.

Other Metafer Modules

Lists various upgrades and modules for Metafer, including CometScan, VSlide, and analysis stations.

Accessories

Neon Accessories

Lists accessories related to Neon, such as Case Data Management and Barcode Software upgrade.

Metafer Accessories

Details accessories for Metafer like Automated SlideFeeder and AutoOiler Module.

Hardware Components

Core System Components

Lists essential hardware: PC, mouse, monitor, and scanning stage.

Camera and Monitor Packages

Details specific camera and monitor packages available for Metafer systems.

Instructions for Use

How to Complete the First Scan

Guides on starting Metafer software, connecting hardware, and initiating the first scan.

Operating Modes and Setup

Explains selecting operational modes, defining search parameters, and initiating the search process.

Instructions for Use - Scan Results and Exiting

Relocating Objects and Loading Scans

Details how to relocate detected objects and load previous search runs.

Exiting Metafer and Neon

Provides instructions for printing reports, saving scans, and properly exiting the software.

Microscopes

Microscope Connectivity and Support

Explains microscope connection requirements and software support for motorized microscopes.

Köhler Illumination Procedure

Details the step-by-step procedure for achieving Köhler illumination for optimal image quality.

Troubleshooting

System Not Working or Monitor Issues

Addresses common problems like system failure, power interruptions, and monitor display issues.

Hardware Initialization Errors

Troubleshoots non-responding hardware components during software initialization.

Stage Range and Live Image Issues

Resolves errors related to stage axis exceeding range and missing live images.

Troubleshooting - Image and Print Issues

Live Image Brightness and Focus

Diagnoses issues with dark live images and difficulties with manual focusing.

Image Contrast and FISH Signals

Addresses problems with poor image contrast and weak FISH signals.

Printing and Disk Space Warnings

Troubleshoots printout failures and warnings related to insufficient disk space.

Troubleshooting - Auto-focus and Image Quality

Auto-focus Malfunctions

Details common causes and solutions when the auto-focus feature does not work properly.

Image Quality Issues

Addresses potential causes for poor image quality, such as artifacts or incorrect settings.

Technical Data

System Dimensions and Weight

Provides specifications for system dimensions, including base plate options, and weight.

Ambient and Operating Conditions

Lists permissible ambient temperatures, humidity, atmospheric pressure, and altitude for operation.

Electrical and Environmental Ratings

Details protection class, electrical safety standards, overvoltage category, and noise immunity.

Power Consumption and Line Requirements

Specifies power consumption, line voltage ranges, and line frequency for the system.

MetaSystem Metafer Specifications

General IconGeneral
CategoryLaboratory Equipment
ModelMetafer
AutomationFully Automated
TypeMicroscope
ManufacturerMetaSystem
ApplicationCytogenetics, Pathology
CameraHigh-resolution digital camera
SoftwareMetafer software suite
Light SourceLED
StageMotorized stage for automated slide scanning
Scanning MethodAutomated slide scanning
CompatibilityCompatible with various slide formats