14
u
Procedure G — Test the Integrity of the Cadence ILC Module
This procedure includes steps to test the Cadence setup for leaks.
Follow these steps to test the integrity of the Cadence ILC module:
1. Open the feed and permeate 2 lines and close the retentate and permeate 1 line.
2. Direct the permeate line to collection vessel or drain.
3. Restart the system pump or reopen the compressed air source and adjust to maintain a feed
pressure of:
– Delta membranes: 4.1 barg (60 psig)
– Omega membranes: 2.1 barg (30 psig)
CAUTION!
Do not exceed the pressure rating of the tubing during operation or integrity
testing. Tubing that is rated to at least 4.1 bar (60 psi) should be used.
4. Measure the air flow out of the permeate port using the Pall Flowstar integrity tester or other
integrity test equipment.
5. If the flow from the permeate port is less than the values stated in Table 3,
the Cadence ILC module is integral. If the flow from the permeate port is greater than
these values, the module has failed the integrity test. If a module fails the integrity test, please
contact Pall for further assistance.
6. Stop the compressed air source or pump and gradually depressurize the module by slowly
opening the retentate line valve.
Table 3
Integrity test parameters for Cadence ILC devices
Forward Flow Limit
Part Number Membrane Type Test Pressure Filter Area
(m
2
)
(sccm)
ILD010T010407 Delta, 10 kDa 4.1 barg (60 psig) 0.065 35
ILD010T020407 0.13 70
ILD010T120407 0.7 380
ILD010T060407 3.5 1900
ILD030T010407 Delta, 30 kDa 0.065 35
ILD030T020407 0.13 70
ILD030T120407 0.7 380
ILD030T060407 3.5 1900
ILOS010T010407 Omega, 10 kDa 2.1 barg (30 psig) 0.065 100
ILOS010T020407 0.13 210
ILOS010T120407 0.7 1100
ILOS010T060407 3.5 5600
ILOS030T010407 Omega, 30 kDa 0.065 100
ILOS030T020407 0.13 210
ILOS030T120407 0.7 1100
ILOS030T060407 3.5 5600