Pall Cadence ILC User Manual

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Contents
1. Important Information ...............................................................................................................................3
1.1 Safety Notice ........................................................................................................................................3
1.2 Application of the Care and Use Procedures .......................................................................................4
1.3 Using the Cadence Inline Concentrator (ILC) Module Safely ................................................................4
1.4 Locating Safety Information ..................................................................................................................5
1.5 Environmental Compliance ...................................................................................................................5
1.6 Where to Get Help ...............................................................................................................................5
2. Learning about the Cadence Inline Concentrator Module ....................................................................6
2.1 Cadence ILC Module ...........................................................................................................................6
2.2 Cadence ILC Module Information .........................................................................................................6
2.3 Cadence ILC Module Port Locations....................................................................................................6
3. Application of Single-Pass Tangential Flow Filtration.............................................................................7
3.1 Process Variables .................................................................................................................................7
3.2 Proper Use...........................................................................................................................................7
4. An Overview of Cadence ILC Processing ...............................................................................................7
4.1 The Four Parts of a Single-Pass TFF Process ......................................................................................7
5. Using the Cadence ILC Module ...............................................................................................................9
5.1 Preparation: Equipment and Materials..................................................................................................9
5.2 Part 1 — Pre-Use Conditioning ..........................................................................................................10
Procedure A — Connect the Cadence ILC Module to the Tubing ......................................................10
Procedure B — Flush the Cadence ILC Module with Purified Water ..................................................10
Procedure C — Sanitize the Cadence ILC Module ............................................................................11
Procedure D — Flush the Cadence ILC Module with Purified Water ..................................................11
Procedure E — Determine Cadence ILC Module Normalized Water Permeability (NWP) ....................12
Procedure F — Determine the Hold-Up Volume of the Cadence Setup and Module ..........................13
Procedure G — Test the Integrity of the Cadence ILC Module ..........................................................14
Procedure H — Flush with Buffer ......................................................................................................15
5.3 Part 2 — Processing ..........................................................................................................................15
Procedure I — Process Product ........................................................................................................15
Procedure J — Recover Product from the Cadence ILC Module........................................................15
5.4 Part 3 — Post-Use Conditioning ........................................................................................................16
Procedure K — Clean the Cadence ILC Module ................................................................................16
Procedure L — Flush the Cadence ILC Module with Purified Water ...................................................17
Procedure M — Determine Cadence ILC Module Normalized Water Permeability (NWP) ...................17
Procedure N — Test Integrity of the Cadence ILC Module .................................................................17
Procedure O — Add Storage Solution to the Cadence ILC Module ...................................................17
5.5 Part 4 — Post-Use Disposal ..............................................................................................................18
6. Appendices..............................................................................................................................................18
6.1 Recommended Storage of New Cadence ILC Modules .....................................................................18
6.2 Delta and Omega Membranes Chemical Compatibility .......................................................................18
6.3 Alternative Chemical Agents ..............................................................................................................18

Pall Cadence ILC Specifications

General

Brand	Pall
Model	Cadence ILC
Category	Water Filtration Systems
Language	English