REPLIGEN OPUS 14 - Solvent Compatibility; Table 4. Product Materials and Quality Standards; Table 5. Solvent Compatibility for OPUS Columns

UG-OPUS® 5-80R
9
OPUS® 5-80R Pre-packed Chromatography Columns
Table 4. Product Materials and Quality Standards
Component Material USP CFR 21 177 BSE/TSE
OPUS® 45R, 60R, 80R cm IDs
Composite tube
70% w/w E-Glass
/ PP*
Homopolymer
Class VI
USP <88>
177.1520 Animal Free
Column Tubes
OPUS® 5-30 cm IDs
Extruded PP
Homopolymer
Class VI
USP <88>
177.1520 Animal Free
Flow Distributors
OPUS® 5 – 80R
Inlet and Outlet Ports, OPUS® R Plug,
OPUS® R Inside Port
Compression
Molded PP*
Homopolymer
Class VI
USP <88>
177.1520 Animal Free
Bed Support Screens
OPUS® 5-80R
PP* Woven Mesh
Class VI
USP<88>
177.1520 EMA 410/01
Flow Distributor O-Rings, OPUS® R
Plug O-Ring, OPUS® R Inner/Outer
Gaskets
Platinum Cured
Silicone (PCS^ O-
rings)
Class VI 177.2600 Animal Free
Return Line Tube,
OPUS® 10-80R
Platinum Cured
Silicone
(PCS^ braided
tubing)
Class VI 177.2600 Animal Free
*PP = Polypropylene
^PCS = Platinum Cured Silicone
2.7 Solvent Compatibility
The product contact materials of construction consist of polypropylene and silicone parts. Table 5
lists common solutions with excellent compatibility with both polypropylene and silicone.
Table 5. Solvent Compatibility for OPUS
® Columns
Solvent Compatibility
Water
Citric Acid
20% Acetic Acid
Methanol
20% Ethanol
Phosphoric Acid
10% Acetone
Hydrochloric Acid (<20%)
2% (w/v) Detergents
Sulfuric Acid (<50%)
8M Urea or 6M Guanidine HCl
2M Sodium Hydroxide
Potassium Hydroxide
Benzyl Alcohol
Isopropyl Alcohol (IPA)