REPLIGEN OPUS 14 - Default Chapter; Table of Contents

Table of Contents
1 Safety Notices ...................................................................................................................... 4
2 Introduction ......................................................................................................................... 4
2.1 What is Open Platform User Specified (OPUS®)? ...................................................................... 4
2.2 Column Design ........................................................................................................................... 4
2.3 Platformable .............................................................................................................................. 5
2.4 Materials of Construction .......................................................................................................... 5
2.5 OPUS® Physical Specifications ................................................................................................... 7
2.6 Product Contact Materials ......................................................................................................... 8
2.7 Solvent Compatibility ................................................................................................................. 9
2.8 Column Mass Table .................................................................................................................. 10
2.9 OPUS® Column Handling .......................................................................................................... 10
3 Preparing to Use Your OPUS® Column ................................................................................. 10
4 OPUS® Column Sanitization, Storage, and Disposal .............................................................. 13
4.1 Cleaning and Sanitization Notes .............................................................................................. 13
5 Troubleshooting ................................................................................................................. 13
5.1 Air in the column ...................................................................................................................... 13
5.2 High pressure during first use of column ................................................................................. 13
5.3 Pressure increase during run ................................................................................................... 14
5.4 Pressure drop during run ......................................................................................................... 14
6 Appendices......................................................................................................................... 15
6.1 Appendix 1: Use of a 3-Way Valve for Inlet Connection and Air Purging ................................ 15
6.2 Appendix 2: Connecting an OPUS® column to Chromatography Skids ................................... 16
6.3 Appendix 3: Column Performance Testing .............................................................................. 16
Index ......................................................................................................................................... 19