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Thermo Scientific Dionex ICS-1100 User Manual

Thermo Scientific Dionex ICS-1100
168 pages
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Dionex ICS-1100 Ion Chromatography
System Operators Manual
Document No. 065289
Revision 03
October 2012

Table of Contents

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Thermo Scientific Dionex ICS-1100 Specifications

General IconGeneral
TypeIon Chromatography System
TechnologyCapillary Ion Chromatography
DetectorConductivity Detector
Data SystemChromeleon Chromatography Data System
Pressure RangeUp to 5000 psi
Power Requirements100-240 VAC, 50/60 Hz
Communication InterfaceUSB, Ethernet
Sample Injection VolumeUp to 25 µL
Injection VolumeUp to 25 µL
Flow Rate Range0.00 to 5.00 mL/min

Summary

1 • Introduction

1.1 Introduction to Ion Chromatography (IC)

Explains ion analysis and the Dionex ICS-1100 system's function and components.

1.2 Overview of the Dionex ICS-1100

Provides a general description of the Dionex ICS-1100 system, its components, and capabilities.

1.3 About This Manual

Details the manual's electronic features and outlines the content of each chapter and appendix.

1.4 Safety and Regulatory Information

Covers manufacturing details, intended use, and safety/regulatory compliance labels and standards.

2 • Features

2.1 Operating Features

Describes key features of the Dionex ICS-1100, including the front panel, top cover, and component panel.

2.2 Flow Schematics

Illustrates the liquid flow path for standard and RFIC-ER configurations.

2.3 Chromeleon and Chromeleon Xpress

Explains control via Chromeleon software, including panel tabsets and software control modes.

2.4 System Component Details

Provides detailed descriptions of individual system components.

3 • Operation and Maintenance

3.1 Operation Overview

Presents a flowchart of the basic steps for routine operation of the Dionex ICS-1100.

3.2 Turning On the System Power

Details the procedure for powering on the Dionex ICS-1100, computer, and autosampler.

3.3 Connecting to Chromeleon

Guides on how to start and connect the Dionex ICS-1100 to the Chromeleon software.

3.4 Set Up the Eluent Reservoir

Provides instructions for preparing, degassing, filtering, and filling the eluent reservoir.

3.5 Check All Connections

Ensures proper filling of the eluent reservoir and secure tubing connections.

3.6 Prime the Pump

Describes the procedure for priming the pump, including line priming and pump head priming.

3.7 Set System Operating Conditions

Covers verifying and setting system operating parameters like flow rate and temperature.

3.8 Equilibrate the System and Verify Operational Status

Explains how to equilibrate the system and verify operational status via background conductivity.

3.9 Prepare Samples

Details sample collection, storage, pretreatment, and dilution procedures.

3.10 Loading and Injecting Samples

Explains techniques for loading samples via syringe or autosampler and injecting them.

3.11 Processing Samples

Covers manual and automatic (batch) sample processing steps using Chromeleon.

3.12 Maintenance

Outlines routine user-performable maintenance tasks, including daily, weekly, and annual checks.

4 • Troubleshooting

4.1 Error Messages

Explains error message icons, severity levels, and their descriptions within the Audit Trail.

4.2 Troubleshooting Error Messages

Provides specific troubleshooting steps for various error conditions and messages.

4.3 Liquid Leaks

Identifies causes and solutions for leaks in fittings, lines, valves, and pump components.

4.4 Pump Difficult to Prime or Loses Prime

Addresses issues with pump priming, relating to eluent, degassing, filters, and blockages.

4.5 Pump Does Not Start

Troubleshoots reasons for the pump failing to start, including power, communication, and settings.

4.6 No Flow

Diagnoses issues causing no flow, such as open valves, unprimed pumps, or broken pistons.

4.7 Erratic Flow/Pressure Reading

Covers causes of erratic readings, including pump priming, seals, check valves, and leaks.

4.8 Excessive System Backpressure

Addresses high backpressure issues due to restrictions in plumbing or fittings.

4.9 Peak “Ghosting”

Explains extraneous peaks in chromatograms and their causes like contamination or injection issues.

4.10 Nonreproducible Peak Height or Retention Time

Troubleshoots issues affecting peak reproducibility, such as column overloading or leaks.

4.11 Abnormal Retention Time or Selectivity

Addresses issues causing abnormal retention times or selectivity, like contaminated eluents.

4.12 No Cell Response

Diagnoses problems with the conductivity cell, including installation and electronics.

4.13 High Cell Output

Explains causes for high cell output, such as suppressor issues or incorrect calibration.

4.14 Baseline Noise or Drift

Covers causes of baseline noise/drift like leaks, trapped gases, contamination, or temperature changes.

4.15 Vacuum Degas Assembly Does Not Run

Troubleshoots the vacuum degas assembly, focusing on Chromeleon settings and calibration.

5 • Service

5.1 Diagnostic and Calibration Procedures

Details diagnostic and calibration procedures performed via the Chromeleon Wellness Panel.

5.2 Isolating a Restriction in the Liquid Lines

Provides methods to identify and isolate restrictions causing excessive system backpressure.

5.3 Replacing Tubing and Fittings

Lists tubing sizes and types, and procedures for replacing tubing and fittings.

5.4 Rebuilding the Injection Valve or Auxiliary Valve

Explains the annual recommendation for rebuilding injection and auxiliary valves.

5.5 Replacing an Auxiliary Valve Pod

Describes how to replace the mechanical 'pod' of the optional auxiliary valve.

5.6 Cleaning and Replacing the Pump Check Valves

Covers procedures for cleaning or replacing pump check valves to ensure proper operation.

5.7 Replacing a Pump Piston Seal and Piston Rinse Seal

Details the process for replacing pump piston seals and rinse seals.

5.8 Replacing a Pump Piston

Explains how to replace a pump piston if seals continue to leak after replacement.

5.9 Replacing the Waste Valve or Priming Valve O-Ring

Guides on replacing O-rings in waste or priming valve knobs to fix leaks.

5.10 Replacing the Conductivity Cell

Provides step-by-step instructions for removing and installing a new conductivity cell.

5.11 Replacing the Suppressor

Details the procedure for replacing the suppressor unit with a new one.

5.12 Replacing the Column Heater

Explains the process of removing and installing a new column heater assembly.

5.13 Replacing the Column Heater Heat Exchanger

Provides instructions for replacing the heat exchanger within the column heater.

5.14 Replacing the Eluent Valve

Guides on how to safely disconnect and replace the eluent valve.

5.15 Replacing the Leak Sensor

Details the procedure for replacing the leak sensor if it is faulty.

5.16 Priming the Pump

Covers the two-part procedure for priming the pump, including eluent lines and pump heads.

5.17 Priming the Pump with Isopropyl Alcohol

Describes an alternative priming method using isopropyl alcohol when standard methods fail.

5.18 Changing Main Power Fuses

Explains how to safely replace the main power fuses for the instrument.

A • Specifications

A.1 Electrical

Lists electrical specifications including main power and fuse requirements.

A.2 Physical

Details physical characteristics such as dimensions, weight, decibel level, and control modes.

A.3 Environmental

Specifies operating temperature and humidity ranges for the instrument.

A.4 Front Panel

Describes front panel indicators like Power LED, Inject Valve LEDs, Alarm LED, and Status LEDs.

A.5 Analytical Pump and Fluidics

Lists specifications for the pump type, construction, pressure, flow rate, precision, and accuracy.

A.6 Eluent Regeneration

Details specifications for eluent regeneration, including eluents, flow rates, and operation.

A.7 Detector Electronics

Covers specifications for the detector electronics, including type, cell drive, linearity, and resolution.

A.8 Conductivity Cell with Heat Exchanger

Lists specifications for the conductivity cell and its heat exchanger.

A.9 Injection Valve

Specifies details about the injection valve, including type and ports.

A.10 Auxiliary Valve (Optional)

Details specifications for the optional auxiliary valve.

A.11 Vacuum Degas Assembly (Optional)

Lists specifications for the optional vacuum degas assembly.

A.12 Column Heater (Optional)

Provides specifications for the optional column heater.

A.13 Suppressors

Details specifications for various types of suppressors, including capacity and control range.

A.14 Autosampler

Lists specifications related to autosampler compatibility and features.

A.15 System Software

Covers specifications for the system software, including Chromeleon and its features.

B • TTL and Relay Control

B.1 TTL and Relay Connections

Describes the TTL/relay connector strip and pin assignments for external device control.

B.2 Controlling TTL and Relay Outputs

Explains how to control TTL outputs and relay contacts for external device functions.

C • Reordering Information

D • FAQ

D.1 How do I hook up an autosampler?

Provides guidance on connecting an autosampler to the Dionex ICS-1100.

D.2 How do I print?

Instructions on how to print from the Chromeleon software.

D.3 Why are the retention times moving?

Explains factors causing retention time shifts, such as pump flow or column contamination.

D.4 How do I adjust retention times?

Discusses adjusting retention times using Chromeleon parameters for time drifts.

D.5 When should I remake standards?

Advises on the frequency of remaking calibration standards.

D.6 When should I remake eluents?

Provides guidance on how often eluents should be remade.

D.7 How do I start Chromeleon?

Instructions on launching the Chromeleon software application.

D.8 How do I delete data?

Explains how to delete sequences or data within Chromeleon.

D.9 How do I back up data?

Details the process for backing up data from Chromeleon.

D.10 How do I shut off the system?

Describes the procedure for safely shutting down the system.

D.11 How do I store columns?

Provides guidance on the proper method for storing chromatographic columns.

D.12 How do I know when a column is dirty?

Directs users to column manual troubleshooting for identifying dirty columns.

D.13 How do I clean a column?

Refers users to the column manual for instructions on cleaning columns.

D.14 Why is the conductivity high?

Lists common reasons for high conductivity readings, including suppressor and calibration issues.

D.15 How do I configure and operate the auxiliary valve?

Refers to a specific manual for configuring and operating the auxiliary valve.

E • Glossary

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