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Reaction Sequence
Uric Acid (URIC)
Uric acid determinations are useful in avian patients and dalmatians in place of urea determinations.
In all dogs (except dalmatians) with diffuse hepatic disease, there is marked elevation of blood uric
acid above the normal levels of <1 mg/dL.
Principal Reason for Performing the Test
As an indicator of the severity of renal disease in avian populations (and dalmatians).
Most Common Abnormality Indicated by the Test
Increased uric acid—prerenal, postrenal, and renal azotemia associated with decreased glomerular
filtration rate.
Sample Type and Precautions
Remove plasma or serum promptly from the cells or clot. If plasma is collected, use only lithium
heparinized samples. Plasma collected from sodium fluoride, citrate, or EDTA preservative should
not be used.
Complementary Tests
Creatinine, UCRE/CREA, UPRO
Reaction Sequence
Urine Creatinine (UCRE)
Urine creatinine is determined so that the concentration of electrolytes filtered or lost through the
glomeruli or renal tubules, such as urinary protein or cortisol, can be quantitated, compared, and
expressed as ratios with diagnostic significance.
Appendices