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Principal Reason for Performing the Test
To be performed with urine protein in order to determine the urine protein:creatinine ratio (UPC).
Most Common Abnormality Indicated by the Test
Proteinuria indicating early renal disease, protein-losing nephropathy.
Sample Type and Precautions
Urine, preferably collected through cycstocentesis, collected in a clean container. An inactive
urinary sediment should be demonstrated and urinary tract infection (UTI) via culture and sensitivity
should be ruled out before performing, as UTI may mildly to moderately raise the UPC.
Complementary Tests
Complete urinalysis with culture and sensitivity. Serum chemistries, such as creatinine, BUN,
albumin, and globulin.
CBC
SNAP* 4Dx* Test
Storage Information
Handle and store urine samples in closed containers to avoid evaporation and contamination.
Samples may be stored at room temperature for up to 3 days (refrigeration preferred). Frozen
samples can be stored indefinitely.
Reaction Sequence
Urine Protein (UPRO)
Urinary protein is determined and compared to the concentration of creatinine in order to assess
the level of renal protein (glomeruli and tubular) loss to determine the urine protein:creatinine (UPC)
ratio.
Principal Reason for Performing the Test
To be performed with urine creatinine in order to determine the urine protein:creatinine (UPC) ratio.
Most Common Abnormality Indicated by the Test
Proteinuria indicating early renal failure, protein-losing nephropathy.
Sample Type and Precautions
Urine, preferably collected through cycstocentesis, collected in a clean container. An inactive
urinary sediment should be demonstrated and urinary tract infection (UTI) via culture and sensitivity
should be ruled out before performing as UTI may mildly to moderately raise the UPC.
Appendices
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