SARA-G450 - System integration manual 
UBX-18046432 - R08  Design-in  Page 113 of 143 
C1-Public     
☞  Any external signal connected to the GPIOs must be tri-stated or set low when the module is in 
power-off mode and during the module power-on sequence (at least until the settling of the V_INT 
supply output of the module to the configured 1.8 V / 3 V value), to avoid latch-up of circuits and 
allow  a  clean  boot  of  the  module.  If  the  external  signals  connected  to  the  module  cannot  be 
tri-stated  or  set  low,  insert  a  multi-channel  digital  switch  (e.g.  Texas  Instruments 
SN74CB3Q16244, TS5A3159, or TS5A63157) between the two-circuit connections and set to high 
impedance during module power-off mode and power-on sequence. 
☞  If the GPIO pins are not used, they can be left unconnected on the application board. 
 
2.8.1.2  Guidelines for GPIO layout design 
The general purpose input/output pins are generally not critical for layout. 
 
2.9  Reserved pins (RSVD) 
SARA-G450 modules have pins reserved for future use, marked as RSVD. 
All the RSVD pins can be left unconnected on the application board, except for the RSVD pin #33 that 
can be externally connected to GND or left unconnected too. 
 
2.10  Module placement 
Optimize placement for minimum length of RF line and closer path from DC source for VCC. 
Make sure that the module, RF and analog parts / circuits are clearly separated from any possible 
source of radiated energy, including digital circuits that can radiate some digital frequency harmonics, 
which  can produce  electromagnetic  interference  affecting  module,  RF and  analog  parts  /  circuits’ 
performance  or  implement  suitable  countermeasures  to  avoid  any  possible  electromagnetic 
compatibility issue. 
Make  sure  that  the  module,  RF  and  analog  parts  /  circuits,  high  speed  digital  circuits  are  clearly 
separated from any sensitive part / circuit which may be affected by electromagnetic interference or 
employ countermeasures to avoid any possible electromagnetic compatibility issue. 
Provide enough clearance between the module and any external part: clearance of at least 0.4 mm per 
side is recommended to let suitable mounting of the parts. 
☞  The heat dissipation during transmission at maximum power can raise the temperature of the 
module and its environment, as the application board locations near and below the SARA-G450 
modules: avoid placing temperature sensitive devices close to the module.