48 Agilent 6400 Series Triple Quad LC/MS Concepts Guide
3 Agilent Triple Quadrupole MS and Sensitivity
Agilent Jet Stream Technology
Agilent Jet Stream thermal gradient focusing consists of a
superheated nitrogen sheath gas that is introduced collinear
and concentric to the pneumatically assisted electrospray.
Thermal energy from the superheated nitrogen sheath gas is
focused to the nebulizer spray producing the most efficient
desolvation and ion generation possible. The enhanced
molecular ion desolvation results in more ions entering the
sampling capillary as shown in Figure 22 and concomitant
improved signal to noise. Parameters for the Agilent Jet Stream
Technology are the superheated nitrogen sheath gas
temperature and flow rate and the nozzle voltage.
The capillary in the 6490A is a resistive capillary that improves
ion transmission. It has 6 capillary inlets and samples up to 10X
more ion rich gas from the source.
Figure 22 Electrospray Ion Source with Agilent Jet Stream Technology
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