Devicor Neoprobe neo2000 - 6. POTENTIAL APPLICATIONS; External Application Examples; Intraoperative Lymphatic Tissue Localization

neoprobe
TM
GDS Operation Manual
AW-000639 Page 19 of 38
ITEM
DESCRIPTION
CAUTION: non-sterile
WARNING: hazardous voltage or shock hazard present; follow instructions and warnings
Devicor uses recyclable materials wherever possible. There are materials in our
product that do contain risk associated with Disposal. If the need arises that
components, parts, accessories or devices at end of life need to be disposed of, we
recommend that you comply with local, state and/or international laws and
regulations for your country or area.
6. POTENTIAL APPLICATIONS
Product is used transcutaneously and intracutaneously to detect radioactive emissions from body tissues or organs
where radiopharmaceuticals are administered. Most commonly administered isotopes are listed in following table, all
are detected by this product.
Radionuclide
Principal
Photo peak Energy
(keV)
Physical Half-Life
Select this Radionuclide
Indicator
 Iodine-125
27-35, Te X-rays
60 days
125
I
 Cobalt-57
122
270 days
57
Co
 Technetium-
99m
140
6.02 hrs.
99m
Tc
 Indium-111
171/245
2.83 days
111
In
 Iodine-131
364
8.07 days
131
I
 Flourine-18
511
110 min.
18
F
NOTE: A variety of radiopharmaceuticals are available. It is responsibility of user to determine suitability and
clinical utility of chosen radiopharmaceutical or radiolabeled compound, and protocol for administering drug and
using probe intracutaneously.
External application
External gamma detection of administered isotope provides noninvasive means of gathering important physiological
and/or anatomical information. Some examples are: detection and localization of blood clot formulation using
125
I or
111
In labeled platelets: evaluation of thyroid function by measuring radioactive iodine uptake; evaluation of skin or
skeletal muscle blood flow; diagnosis of testicular torsion using
99m
Tc; intracutaneous scanning for localization of
lymphatic tissue.
Intraoperative localization of lymphatic tissue
Lymphoscintigraphy is a common medical procedure employed to define lymphatic flow from a site of injection
through lymphatic tissue. Hand-held gamma probes may be useful in assisting a surgeon in localization of regional
lymph node basins draining a lesion site. This allows surgeons to identify areas within lymphatics where a biopsy of
tissue may be taken to determine histological status of lymph tissue.
Artwork No: AW-000639 Revision: A Artwork Status: Released Lifecycle Name: Artwork
PCO No: N/A ECN No: ECN-000214 Release Date: 10/09/2012 Effective Date: 10/09/2012