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10. Draining
D
raining can be performed in a number of ways according to the specific application requirements.
Table 1 below gives drainage approaches according to application requirements.
Before draining the mixer, follow the below instructions:
1
. Connect the outlet port to the desired downstream equipment or receptacle according to the specific
fitting on the single-use system (e.g. Kleenpak sterile connector or quick connector).
2. Open the outlet port valve by gently rotating the flush port bayonet valve to a stop, allowing fluid to
flow out of the Allegro mixer biocontainer.
CAUTION! Take care to not over-rotate, apply excessive force, or pull the flush outlet valve during
operation. This may cause it to detach from the mixer. Use MINIMUM force when rotating the bayonet
valve to open the outlet line.
Table 1
Draining the mixer system
Mixer rotation ‘Bag Ination’ Setting When to Use Comments
On ON To keep the mixer inated Once the mixer is empty, ‘Bag Ination’
Then OFF Then VENT and to continue mixing can be switched to ‘Vent’ to allow
during dispensing the collapse of the bag prior to removal.
mixed volume Once ‘Vent’ has been selected, the top
of the bag should be gently pushed down
into the mixer tote to free the top hat
from the upper gasket to vent the
biocontainer and allow removal.
OFF ON (until uid dispensed) To keep the mixer inated As above
Then VENT during dispensing the mixed No agitation of uid during dispensing
volume
OFF OFF To allow the mixer to collapse The top of the mixer SU system should
during dispensing the mixed be gently pushed down into the mixer
volume tote to free the top hat from the upper
gasket at the start of the uid dispensing
phase. Allows for removal of the single-
use mixer system as soon as uid
volume is fully dispensed from the system.
Note: Fluid dispensing is normally done using a peristaltic pump on the outlet tubing, especially when a filter is being used down-
stream of the mixer chamber.
The floor of the Perspex tote is specifically designed to
provide very high yield/fluid recovery during draining.
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