Preparing the mass spectrometer for LC operation 2-23
3. Select the correct sample cone for your instrument:
• For the Xevo TQD or SQ Detector 2 instruments, use the 0.50-mm
sample cone, supplied with the instrument, which you stored when
preparing the source ion block for GC operation (see page 2-8,
step 8).
• For all other instruments, use the sample cone that you retained in
the previous procedure (page 2-21, step 6).
4. Carefully slide the sample cone, including its O-ring, into the cone gas
nozzle.
5. Hold the sampling cone assembly so that the cone gas nozzle handle is
oriented horizontally and at the top, and then slide the sampling cone
assembly into the ion block assembly.
6. Grasp the cone gas nozzle handle, and then move the handle downward
from the horizontal to the vertical position to rotate the sampling cone
assembly by 90° degrees (see page 2-5).
7. Open the source isolation valve.
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