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Waters ACQUITY Arc System User Manual

Waters ACQUITY Arc System
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ACQUITY Arc
System Guide
715004747 / Revision A
Copyright © Waters Corporation 2015
All rights reserved

Table of Contents

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Waters ACQUITY Arc System Specifications

General IconGeneral
Wavelength Range (PDA)190 to 800 nm
Wavelength Range (TUV)190 to 400 nm
Data ManagementEmpower Software
Pump TypeQuaternary solvent blending
Gradient Delay Volume650 µL
Autosampler TypeFTN (Flow-Through Needle)
Sample CapacityUp to 96 samples
Injection Volume Range0.1 to 100 µL
Detector OptionsPDA, TUV
Dimensions (W x D x H)Varies by configuration
WeightVaries by configuration
Operating Temperature15°C to 30 °C

Summary

General Information

Copyright Notice

Legal notice regarding copyright ownership and reproduction rights of the document.

Trademarks

List of registered and unregistered trademarks associated with Waters Corporation products.

Customer Comments

Information on how to provide feedback or report errors in the document.

Contacting Waters

Waters Contact Information

Details on how to contact Waters Corporation for technical assistance or inquiries.

Safety Considerations

Safety Hazard Symbol Notice

Explains the meaning and use of safety hazard symbols in documentation.

Power Cord Replacement Hazard

Warning about using the correct type of power cord to avoid electric shock.

Hand Crush Hazard

Warning to keep hands clear of moving parts to avoid crush injuries.

High Voltage Hazard

Precautions to observe regarding high voltage components to avoid electric shock.

Bottle Placement Prohibition

Prohibits placing vessels containing liquid on equipment to prevent shock or fire.

FCC Radiation Emissions Notice

Information regarding compliance with FCC rules for electromagnetic interference.

Electrical Power Safety Notice

Guidance on positioning instruments to ensure easy disconnection of the power cord.

Equipment Misuse Notice

Warning that improper equipment use may compromise safety protections.

General Safety Advisories

Refers to an appendix for a comprehensive list of warning advisories and notices.

Operating the System

Applicable Symbols

Description and meaning of symbols used in instrument manuals and on equipment.

Audience and Purpose

Defines the intended audience and purpose of the system guide.

Intended Use of the ACQUITY Arc System

Details the applications and environments for which the ACQUITY Arc system is designed.

Calibrating

Guidelines for calibrating LC systems using standard curves and acceptable methods.

Quality Control

Procedures for running and evaluating QC samples to ensure system performance.

EMC Considerations

Information related to Electromagnetic Compatibility (EMC) standards and compliance.

Canada Spectrum Management Emissions Notice

Statement of compliance with Canadian emissions standards for digital apparatus.

ISM Classification: ISM Group 1 Class B

Classification of the instrument according to ISM instrument requirements.

EC Authorized Representative

Identifies the authorized representative within the European Community.

Performance Optimization

General Guidelines

Key recommendations for achieving optimum performance and separation in UHPLC analysis.

Carryover

Explanation of carryover in chromatography and methods to minimize it.

Reproducibility

Specifies the precision and reproducibility limits for injection volumes.

Cycle Time (Between Injections)

Methods for reducing cycle time, such as using the Load Ahead option.

Preventing Leaks

Information on preventing leaks in tubing connections and system integrity.

System Maintenance

Contacting Waters Technical Service

Procedures and information required when contacting Waters Technical Service.

Maintenance Procedure and Frequency

Lists periodic maintenance schedules for optimal system performance.

Spare Parts

Guidance on using only Waters Quality Parts to ensure system operation.

Troubleshooting with Connections INSIGHT

Information on using the Connections INSIGHT service for proactive support.

Configuring Maintenance Warnings

How to set up maintenance counters and warnings to minimize downtime.

External Connections

External Wiring and Plumbing Connections

Overview of connecting chromatographic tubing and system components.

External Wiring Connections

Diagrams and details for rear-panel wiring connections between modules.

Plumbing Connections

Diagrams illustrating the plumbing connections for system modules.

Waste-Tubing Connections

Illustrations showing the proper routing of waste and condensate tubing.

Connecting to the Electricity Source

Instructions for connecting modules to a grounded power source.

Connecting Signal Cables

Details on connecting signal cables using appropriate tools and materials.

Ethernet Connections

Guidance on connecting system modules and the PC via Ethernet.

Safety Advisories

Warning Symbols

Identifies hazard symbols and their associated risks (death, injury, adverse reactions).

Specific Warnings

Provides specific safety warnings, such as burst warnings for nonmetallic tubing.

Biohazard Warning

Warning concerning handling of biological agents and infectious materials.

Biohazard and Chemical Hazard Warning

Warning related to handling biohazards, toxic, or corrosive materials.

Notices

Alerts to potential damage or integrity compromise, often with an exclamation point symbol.

Bottles Prohibited Symbol

Warns of equipment damage risk from solvent spills and proper bottle placement.

Required Protection

Highlights the need for personal protective equipment like eye protection and gloves.

Warnings Applicable to All Waters Instruments

General warnings about operating equipment not specified by the manufacturer.

Warnings for Replacing Fuses

Safety instructions and guidance for replacing fuses in instruments.

Electrical Symbols

Description of electrical symbols found on instruments and in manuals.

Handling Symbols

Explanation of symbols used on packaging for shipping and handling instructions.

Solvent Considerations

Preventing Contamination

Information on preventing contamination in LC/MS and HPLC/MS systems.

Clean Solvents

Importance of using clean solvents for reproducible results and minimal maintenance.

Solvent Quality

Recommendations for solvent grade (MS or HPLC) and filtration.

Solvent Preparation

Guidance on proper solvent preparation, primarily filtration, to prevent pumping issues.

Water

Recommendations for using high-quality water and preventing microbial growth.

Using Buffers

Instructions for preparing and using buffers, including flushing procedures.

Common Solvent Properties

Solvent Miscibility

Guidance on determining solvent miscibility for changing mobile phases.

Using Miscibility Numbers (M-numbers)

Explanation of M-numbers for predicting miscibility of liquids.

Solvent Stabilizers

Information on solvent stabilizers and precautions for handling them.

Solvent Viscosity

Discussion on the role of solvent viscosity in gradient chromatography.

Wavelength Selection

Guidance on selecting wavelengths for optimal detection and reduced baseline noise.

UV Cutoffs for Common Solvents

Table of UV cutoff wavelengths for common chromatographic solvents.

Mixed Mobile Phases

Provides approximate wavelength cutoffs for various solvents, buffers, and mobile phases.

Mobile Phase Absorbance

Lists mobile phase absorbances at different wavelengths to help reduce baseline noise.

Specifications

System Specifications

Key performance specifications for the ACQUITY Arc system as a whole.

Quaternary Solvent Manager-R Specifications

Detailed technical specifications for the QSM-R module.

Sample Manager FTN-R Specifications

Detailed technical specifications for the SM FTN-R module.

30-cm Column Heater and 30-cm Column Heater/Cooler Specifications

Specifications for the 30-cm Column Heater and Heater/Cooler modules.

30-cm Column Heater-Active (CH-30A) Specifications

Specifications for the optional 30-cm Column Heater-Active module.

Instrument Control Specifications

Specifications related to informatics compatibility and communications.

Environmental Specifications

Operating environmental ranges including temperature and humidity.

Electrical Specifications

Technical specifications for power requirements and line frequency.

Physical Specifications

Dimensions and weight specifications for the ACQUITY Arc system.

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