Waters APGC - Preparing the Source Ion Block for LC Operation

2-22 Setting up the APGC
location. For all other instruments, retain the sample cone for use in the
next procedure.
Store all other APGC components in a safe location.
Preparing the source ion block for LC operation
Required materials
• Chemical-resistant, powder-free gloves
• Combined, 2.5-mm Allen wrench and cone extraction tool
Requirement: During LC operation with the Xevo TQD or SQ Detector 2
instrument, you must use the original, 0.50-mm, sample cone supplied with
the instrument, to avoid problems associated with low sensitivity.
To prepare the source ion block for LC operation:
1. Use the 2.5-mm, combined Allen wrench and cone extraction tool to fit
and tighten the screw and washers securing the upper, gas-cone position
block to the ion block assembly (see page 2-8).
2. Repeat step 1 for the lower, gas-cone position block.
Warning: To avoid personal contamination with biologically
hazardous, toxic, or corrosive materials, and to avoid
spreading contamination to uncontaminated surfaces, wear
clean, chemical-resistant, powder-free gloves when handling
source components.
Warning: To avoid burn injuries, take great care while
working with the source components, which can be hot.
Caution: To avoid damaging the instrument by sudden
venting, do not open the source isolation valve before the
sampling cone assembly is securely fitted to the ion block
assembly.