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Agilent Technologies
Agilent 6400 Series Triple Quadrupole LC/MS System
Concepts Guide
2
Inner Workings – Triple Quadrupole MS
versus Single Quadrupole MS
Single quadrupole MS operation 14
Design for a single quadrupole mass spectrometer 14
How a single quadrupole mass spectrometer works 15
Triple quadrupole MS operation 21
Design of the Agilent Triple Quadrupole MS 21
How a triple quadrupole mass spectrometer works 27
Innovative Enhancements in the 6490 Triple Quadrupole 23
Innovative Enhancements in the 6460 Triple Quadrupole 25
Innovative Enhancements in the 6430 Triple Quadrupole 27
How Dynamic MRM works 30
How Triggered Dynamic MRM works 33
In this chapter you learn about concepts to help you understand
the inner workings of the Agilent 6400 Series Triple Quadrupole
LC/MS.
The foundation for understanding the operation of a triple
quadrupole mass spectrometer is the operation of a single
quadrupole mass spectrometer. Therefore, an explanation of the
workings of a single quadrupole mass spectrometer is presented
first.
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