24 Agilent 6400 Series Triple Quad LC/MS Concepts Guide
2 Inner Workings – Triple Quadrupole MS versus Single Quadrupole MS
Innovative Enhancements in the 6490 Triple Quadrupole
Ions are generated using an electrospray ion source where the
analyte is simultaneously ionized and desolvated from the
liquid matrix. The iFunnel includes the application of Agilent
Jet Stream Technology (first introduced with the 6460) which
improves sensitivity via thermal gradient focusing and
enhanced desolvation.
The first innovative enhancement is the use of a short hexabore
capillary. It has 6 capillary inlets and samples up to 10X more
ion rich gas from the source. It captures the majority of the gas
from the source region. See Figure 10. The hexabore capillary
transmits a high gas/ion volume into the ion optic system.
Figure 9 The iFunnel Technology
Figure 10 Hexabore capillary
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