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MSD MESO QuickPlex SQ 120 User Manual

MSD MESO QuickPlex SQ 120
42 pages
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INSTRUMENT MANUAL
www.mesoscale.com
®
MESO
®
QuickPlex
SQ 120

Table of Contents

Questions and Answers:

MSD MESO QuickPlex SQ 120 Specifications

General IconGeneral
TechnologyElectrochemiluminescence (ECL)
Dynamic RangeUp to 6 logs
Multiplexing CapabilityUp to 10 analytes per well
Sample Volume25-50 µL
Plate Format96-well
Weight20.4 kg
Power Requirements100-240 V, 50/60 Hz
Assay Time1-3 hours, depending on assay

Summary

Introduction

Intended Audience

Defines target users and their required background knowledge.

How to Use This Manual

Explains manual organization, structure, and hyperlinked elements.

Warnings and Caution Symbols

Details warning and caution symbols used in the manual and their meanings.

Formatting Information

Outlines text formatting conventions used throughout the manual for clarity.

Safety Information

Regulatory and Safety Certifications

Lists regulatory compliance standards and certifications for the instrument.

Laser Safety

Classifies the instrument's laser components and compliance with laser safety standards.

WEEE Compliance

States compliance with the Waste Electrical and Electronic Equipment directive.

Hazardous Substances

Details hazardous substances present in instrument parts and their environmental protection use period.

Symbols and Labels

Defines various symbols and labels used in the manual and on the instrument.

General Operation

Provides guidelines for general operation, including standby mode and environmental conditions.

Electrical Hazards

Addresses electrical safety precautions, including power supply and hazardous atmospheres.

Chemical and Biological Hazards

Details precautions for handling chemicals, biological materials, and potential exposures.

Laser and Barcode Reader Safety

Warns about laser hazards and proper operation of the barcode reader.

Mechanical Hazards

Covers mechanical hazards, including instrument weight and moving parts.

ESD Sensitivity Precautions

Explains electrostatic discharge sensitivity and recommended precautions.

Electromagnetic Interference and Susceptibility

Discusses compliance with FCC rules and precautions against interference.

Software and OS Compatibility

Advises on compatibility issues with Windows updates and other software.

Decontamination Procedures

Outlines procedures for decontaminating the instrument before shipping or service.

System Description

Intended Use

States the instrument's purpose for research use only, not diagnostic procedures.

Specifications Overview

Provides a summary of the instrument's performance and plate reading capabilities.

Plate Compatibility

Lists the types of plates compatible with the QuickPlex SQ 120 instrument.

System Components

Lists the essential components that make up a standard QuickPlex SQ 120 system.

MESO QuickPlex SQ 120 Instrument Components

Details the main components of the QuickPlex SQ 120 instrument itself.

CCD Camera and Telecentric Lens

Describes the imager's camera and lens system for detecting emitted light.

Motion Control System

Explains the mechanism for transporting plates within the instrument.

Plate Barcode Reader

Details the function of the internal barcode reader for plate identification.

Integrated Assay Plate Stacker

Describes the plate loading and unloading mechanism and its capacity.

Status LEDs

Explains the meaning of the status indicator lights on the imager's camera tower.

Power Switch and I/O Panel

Locates and describes the instrument's power switch, ports, and connections.

Compatible Computer System

Details the computer system configuration and its role in the instrument setup.

DISCOVERY WORKBENCH Software

Introduces the software application used to operate the instrument and analyze data.

Operational Modes

Describes the different operating modes of the instrument, including stand-alone and robotic integration.

Image Readout Process

Explains how the instrument captures plate images and read times.

Reading Partial Plates

Explains how to configure the instrument to read only specific sectors of a plate.

Electronic Test Plate

Describes the electronic test plate used for verifying system operation and daily checks.

Uninterruptible Power Supply

Recommends using a UPS for data integrity and explains its importance.

Installation, Quick Start, and General Use

System Installation

Outlines the requirements for system installation by a qualified MSD service engineer.

Quick Start Guide

Guides users through running the electronic test plate to verify instrument functionality.

System Start-up

Details the steps for powering on the instrument and starting the software for operation.

Software Setup

Explains how to configure the software for reading the electronic test plate.

Running a Plate Read

Guides users through initiating a plate read using the software's Run Options.

Instrument Operations

Describes the functions of the Pause, Stop, Eject, and Retract buttons for plate movement.

Viewing Assay Results

Explains how to view and interpret assay results using the software's layer views.

Running Multiple Plates

Provides instructions for running multiple plates sequentially and managing output stack capacity.

Robotics Integration

Details how the instrument can be integrated with robotic systems for automated plate handling.

Maintenance

5.1 User Maintenance

Covers basic cleaning and computer maintenance tasks for users.

5.1.1 Computer Maintenance

Recommends periodic maintenance for the computer system to ensure high performance.

5.1.2 Performance Qualification

Mentions the availability of a kit for verifying instrument performance.

5.1.3 Cleaning and Exterior Decontamination

Provides instructions for cleaning spills and general exterior maintenance.

5.2 Preventive Maintenance

Recommends annual preventive maintenance performed by MSD service engineers.

Appendix

6.1 Troubleshooting Guide

Offers solutions to common hardware and operating errors encountered with the instrument.

Instrument Specifications

Provides specific performance, environmental, power, and physical characteristics.

MSD Plate Specifications

Details MSD plate design compliance and barcode label standards.

Technical Support

7.1 Bug Reports and Suggestions

Provides contact information for submitting feedback, bug reports, and feature requests.

Troubleshooting Instrument Problems

Guides users on reporting errors and collecting diagnostic information for troubleshooting.

Contact Information

Lists company headquarters, customer service, scientific support, and instrument service contact details.