Chapter 4 Analog Input
© National Instruments Corporation 4-31 NI USB-621x User Manual
Using the DAQ Assistant, you can configure the channels for referenced 
single-ended or non-referenced single-ended input modes. Refer to the 
Configuring AI Ground-Reference Settings in Software section for more 
information about the DAQ Assistant.
Using Referenced Single-Ended Connections for 
Floating Signal Sources
Figure 4-21 shows how to connect a floating signal source to the 
USB-6210/6211/6212 device configured for referenced single-ended 
mode.
Figure 4-21.  Referenced Single-Ended Connections for Floating Signal Sources
Using the DAQ Assistant, you can configure the channels for referenced 
single-ended or non-referenced single-ended input modes. Refer to the 
Configuring AI Ground-Reference Settings in Software section for more 
information about the DAQ Assistant.
Connecting Ground-Referenced Signal Sources
What Are Ground-Referenced Signal Sources?
A ground-referenced signal source is a signal source connected to the 
building system ground. It is already connected to a common ground point 
with respect to the device, assuming that the computer is plugged into the 
same power system as the source. Non-isolated outputs of instruments and 
devices that plug into the building power system fall into this category.
Selected Channel in RSE Configuration 
PGIA 
Input Multiplexers 
– 
+ 
– 
Floating 
Signal 
Source 
V
s 
I/O Connector 
AI GND 
AI SENSE
AI <0..n> 
+ 
Programmable Gain 
Instrumentation 
Amplifier 
Measured 
Voltage 
V
m 
– 
+