XCell® ATF 2 and 4 Stainless Steel Housings
SG-SSATF24 rev 1
7.4.1 Removing the housing from the bioreactor
1. Stop the permeate/harvest pump and disconnect the harvest bag from the housing.
2. Stop and disconnect the A2C line from the diaphragm pump.
3. Close or disconnect compressed air and vacuum services from the pneumatic enclosure.
4. Disconnect sensors from the filtration assembly to pneumatic enclosure.
5. If necessary, remove the pneumatic enclosure from the filtration assembly.
6. Close both bivalves connecting the filtration assembly to the vessel.
7. Drain liquid from the connection.
8. Optionally, purge the connection with water, steam, or some other medium.
9. Disconnect the filtration assembly from vessel between the two bivalves.
10. Remove the filtration assembly to an appropriate work area.
7.4.2 HFF Removal
1. Drain the system into an appropriate waste vessel or drain.
2. Remove all sensors from the housing.
3. Remove air inlet filter connected to the diaphragm pump and any other connections to the
XCell® ATF Housing.
4. Open the clamp connecting the filter housing to the diaphragm pump and separate.
5. Open the clamp connecting the reducer to the filter housing and separate.
6. Remove the HFF from housing by firmly pressing it from one end.
7. Remove the O-ring at the exposed end of the HFF.
8. Press the HFF in the opposite direction to remove.
9. Prepare filter housing for cleaning and reuse.
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