REPLIGEN XCell ATF 2 - Table of Contents

KrosFlo® TFDF™ Lab System
User Guide
XCell® ATF 2 and 4 Stainless Steel Housings
User Guide
3
SG-SSATF24 rev 1
Contents
6.1.1 Installing the diaphragm ............................................................................................. 10
6.2.1 XCell® ATF 2 Stainless Steel Housing hollow fiber filter installation........................... 11
6.3.1 Filter wetting ............................................................................................................... 12
6.3.2 Integrity testing pre-autoclaving ................................................................................ 12
6.3.3 Autoclaving ................................................................................................................. 12
6.3.4 Integrity testing post-autoclaving ............................................................................... 12
6.4.1 XCell® ATF 2 Stainless Steel tubing set kits and accessories ....................................... 13
6.4.2 Tubing set kit for XCell® ATF 2 Stainless Steel Housing connected to glass bioreactor
14
6.5.1 Removing the housing from the bioreactor ............................................................... 15
6.5.2 HFF Removal ............................................................................................................... 15
6.5.3 Decontaminating the HFF for Disposal ....................................................................... 15
6.5.4 Pump Air Inlet Filter, O-Rings, Gaskets, and Quick Connects ..................................... 15
7.1.1 Installing the diaphragm ............................................................................................. 16
7.1.2 XCell® ATF 4 Stainless Steel Housing hollow fiber filter installation ........................... 17
7.2.1 Pressure testing .......................................................................................................... 18
7.2.2 Filter wetting ............................................................................................................... 18
7.2.3 Integrity testing pre-autoclaving ................................................................................ 18
7.2.4 Autoclaving ................................................................................................................. 18
7.2.5 Integrity testing post-autoclaving ............................................................................... 18
7.3.1 XCell® ATF 4 Stainless Steel Housing tubing set kits and accessories ......................... 19
7.3.2 Tubing set kit for XCell® ATF 4 Stainless Steel Housing connected to glass bioreactor
20
7.4.1 Removing the housing from the bioreactor ............................................................... 21
7.4.2 HFF Removal ............................................................................................................... 21
8.3.1 EU Declaration of Conformity ..................................................................................... 22
8.3.2 Tube set kits ................................................................................................................ 23