XCell ATF Series User Manual

54
XCell
TM
ATF System with C410:V3 Controller
User Guide
Repligen recommends sterilization of the Filtration Assembly by autoclaving. An
appropriately sized autoclave is required. Contact Repligen for dimensional analysis of
the autoclave. Sterilization of the Filtration Assembly by autoclaving is one of the
simplest methods to sterilize the system.
Pre Autoclaving check list:
8.1.1 Thoroughly wet the HFM with appropriate wetting agent
8.1.2 Fully assemble Filtration Assembly as shown in Figure 9.
8.1.3 Perform a pressure test.
8.1.4 Vent all ports blocked with 0.2micron vent filters.
With both the filtrate and retentate sides vented, formation of pressure gradients
across the hollow fibers membranes during sterilization is minimized. This assures
free flow of steam into the unit and unobstructed pressure equilibration between all
compartments within the unit; particularly, the filtrate and retentate sides are at the
same pressure during the sterilization and cool down procedures.
Note: Use high capacity vent filters to allow unobstructed high flow of steam into
and from the system.

XCell ATF Series Specifications

General

Brand	XCell
Model	ATF Series
Category	Laboratory Equipment
Language	English