1st Derivative:
When first derivative is used to recognize the equivalence point, the titration curve inflection point (EQP) is the point where the first
derivative reaches its maximum value.
The detection algorithm looks for the maximum value of the first derivative. The first derivative must be greater than the threshold
value at the maximum point (see Recognition Options section).
2nd Derivative:
When second derivative is used to recognize the equivalence point, the titration curve inflection point (EQP) is the point where the
second derivative crosses zero.
The detection algorithm looks for the point where the second derivative changes sign.
The checked point, or first derivative, must be greater than the threshold value (see Recognition Options section).