IF.UG.IM_R1
3.6 Warnings for System Maintenance
1. Obtain work permits such as lockout/tagout and other permits—per System owner’s safety
procedures before servicing or maintaining the System.
2. Improper opening of the electrical panel and incorrect lockout/tagout can lead to electric
shock resulting in injury or death. To prevent injury or death from electric shock, follow your
company’s lockout/tagout and electrical panel entry procedures.
3. Due to a noise level of 80 decibels or greater, ear protection is required when the System
pumps are operated at a speed of greater than (>) 6000 RPM.
4. If unqualified personnel open and work inside electrical power panels, injury can result from
electric shock. To prevent injury by electric shock, ensure only qualified maintenance
personnel open electrical power panels.
5. Only personnel authorized by Repligen should perform service, installation, and
maintenance inside the System’s electrical panels.
6. To ensure safe and correct operation, use accessories and replacement parts that are
approved or supplied by Repligen.
7. Before inspecting or working on the System using ladders, check and follow local regulations
for fall protection.
8. System must be turned off when replacing fuses to prevent electrical hazard. Any electrical
work beyond the electrical connections procedure and fuse replacement should be
performed by trained personnel only.
9. Opening the flow-paths without flushing them may result in injury from exposure to
hazardous process fluids. To prevent this, purge, flush, and decontaminate the System
before opening flow-paths. Always check the pressure readings on the System HMI to
confirm depressurization has been achieved before performing maintenance activities.
10. Peristaltic pumps must be turned off when replacing either tubing or pump heads to prevent
crushing/pinching hazard.
11. Repligen does not recommend use of Vaporized Hydrogen Peroxide (VHP) to clean the
KrosFlo system.
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