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REPLIGEN KrosFlo SYITF-2000

REPLIGEN KrosFlo SYITF-2000
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User Guide
User Guide
3
IF.UG.IM_R1
Contents
1. Introduction ......................................................................................................................... 7
2. Safety Precautions ................................................................................................................ 7
2.1 Signal Words ........................................................................................................................... 7
2.2 Safety Symbol Icons ................................................................................................................ 8
3. Safety Guidelines .................................................................................................................. 9
3.1 Intended User Guide Audience .............................................................................................. 9
3.2 Intended Use of the System ................................................................................................. 10
3.3 Warnings for Moving, Installing, and Storing the System .................................................... 10
3.4 Warning for System Preparations ........................................................................................ 11
3.5 Warnings for System Operation ........................................................................................... 11
3.6 Warnings for System Maintenance ...................................................................................... 14
4. System Specifications ......................................................................................................... 15
5. System Dimensions ............................................................................................................. 17
6. RoHS and WEEE Compliance ............................................................................................... 17
7. System Overview ................................................................................................................ 18
7.1 Main System ......................................................................................................................... 18
7.2 Cassette Holder Cart (optional) ............................................................................................ 19
7.3 Auxiliary Cart (optional) ........................................................................................................ 19
8. Unpacking the System ........................................................................................................ 20
9. Performing Mechanical Installation ..................................................................................... 21
9.1 Main System Assembly ......................................................................................................... 21
9.2 Cassette Holder Assembly (optional) ................................................................................... 23
9.2.1 Cassettes Installation .................................................................................................. 23
9.2.2 Hydraulic Pump Preparation ....................................................................................... 24
9.3 Single-Use Flow-path Assembly ............................................................................................ 26
9.3.1 Recirculation Pump Preparation and Connections ..................................................... 26
9.3.2 Feed Tank/Reservoir Connections .............................................................................. 30
9.3.3 Installing Auxiliary Pump Tubing ................................................................................. 32
10. Performing Electrical Installation ........................................................................................ 33
10.1 Sensor and Communication Cables ...................................................................................... 33
10.1.1 Pressure Sensors ......................................................................................................... 33
10.1.2 Installing Ferrite Bead for Pressure Sensors ............................................................... 34
10.1.3 Installing Permeate Flow Sensors ............................................................................... 35
10.1.4 Other Sensor and Communication Cables .................................................................. 35
10.1.5 Connecting the System Power Cables ........................................................................ 36
11. Using the System HMI ......................................................................................................... 36
11.1 Human Machine Interface (HMI) Overview ......................................................................... 36
11.2 Getting Started ..................................................................................................................... 37
11.3 Loading and Running Recipes ............................................................................................... 38
11.4 Home Screen......................................................................................................................... 39
11.5 Process Screen ...................................................................................................................... 40
11.6 Alarms Screen ....................................................................................................................... 42
11.7 Diagnostics Screen ................................................................................................................ 43
12. Operating the System ......................................................................................................... 44
12.1 Executing Reports ................................................................................................................. 44
12.2 System Emergency Stop and Responses .............................................................................. 45
12.2.1 Stopping the System Using the E-Stop Button ........................................................... 45
12.2.2 Restarting the System after an Emergency Stop ........................................................ 45
12.3 System Power Loss and Responses ...................................................................................... 46
12.3.1 System Power Loss ...................................................................................................... 46
12.3.2 Restarting the System after a Power Loss .................................................................. 46
12.4 Shutting Down the System ................................................................................................... 46

Table of Contents

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