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REPLIGEN Spectrum KMPi User Manual

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Page #69 background image
69 400-12355-000 Rev. 03
KR2i / KMPi TFF Systems
KF Comm Software
11.2 Installing and Updating TFF System Software and Firmware with KF Comm Software
NOTE: The KF Comm Installation Suite pairs the correct firmwares and softwares for each iteration of
the TFF System's updates. Repligen discourages using firmware and software installed
separately from different KF Comm Installation Suites, as compatibility between the firmware
and software cannot be ensured.
1. Launch “Installer.exe” file from KF Comm folder contents
2. The Spectrum KF Comm Installer will check the system settingspress Proceed to continue
3. Check "Install KF Comm software and workbooks" and "Install USB drivers for pump drive
connection (recommended)." If user is also updating firmware, please select "Update KMPi
Pump" and/or "Update KR2i Pump" depending on which TFF system is being used.
4. Proceed through the default installation steps. When at KF Comm Data Collection Setup's
Custom Setup screen, the user may enable the installer to also install workbooks that
interface with Repligen's Pressure Monitor and KMP components by clicking on the red X
icon and selecting "Will be installed on local hard drive."
5. Complete and confirm installation of all selected components from software suite

Table of Contents

Questions and Answers:

REPLIGEN Spectrum KMPi Specifications

General IconGeneral
ModelSpectrum KMPi
ManufacturerRepligen
ApplicationsTangential flow filtration
Operating PressureUp to 100 psi
Pressure RatingUp to 6 bar (87 psi)
Membrane AreaVariable, depending on module selection
MaterialStainless steel
Data LoggingIntegrated data logging capabilities
ConnectivityEthernet
DimensionsVaries depending on configuration
WeightVaries depending on configuration
CompatibilityCompatible with various TFF membranes

Summary

Safety Precautions

Explanation of Symbols

Explains warning symbols and their meanings, including Danger, Warning, and Caution.

Specifications

KR2i Specifications

Details technical specifications for the KR2i system, including output, input, construction, and environment.

KMPi Specifications

Details technical specifications for the KMPi system, covering output, input, construction, and environment.

System Configuration and Major Components

Setup and Operation

KF Comm Pump Control Interface

Details on using the KF Comm software for system control.

Hardware Setup

Configuring system hardware parameters and settings.

Automated Mode Control Strategy

Defining set-points and control mechanisms for automated processes.

Diafiltration Set Points

Options for controlling diafiltration endpoints.

Concentration Set Points

Options for controlling concentration endpoints.

Pressure Calibration Procedure

Steps for calibrating pressure sensors for accurate readings.

Alarms and Stops Configuration

Setting up safety alarms and operational stops for the system.

System Functionality

Detailed Pump Mode Operation

In-depth explanation of various pump operating modes.

Concentration Mode

Detailed operation of the Concentration Mode.

Concentration/Diafiltration Mode

Operation of the Concentration/Diafiltration Mode.

Constant Feed Concentration Mode

Operation of the Constant Feed Concentration (CFC) mode.

Ctrl Mode Operation

Operation of the Control Mode.

Pump Head Setup and Operation

KR2i Pump Head Operation

Procedures for installing and removing KR2i pump heads.

KMPi Pump Head Operation

Procedures for installing and operating KMPi pump heads.

Auxiliary Component Setup and Operation

Auxiliary Pumps Setup

Connecting and configuring auxiliary pumps.

Automatic Backpressure Valve

Setup and operation of automatic backpressure valves.

KONDUIT System Integration

Integrating the KONDUIT unit with the TFF system.

KF Comm Software

Installing and Updating KF Comm Software and Firmware

Guide to installing and updating system software and firmware.

Troubleshooting

Common Symptoms and Remedies

Identifies common issues and provides solutions.

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