h. Valve 2: Control TMP, Retentate, Inlet or Permeate Pressure
i. KONDUiT: If Concentration or Diafiltration Set-point in Hardware Setup is set to Conductivity
or UV set-points, then KONDUiT signals when pump mode ends
8.2 Detailed Pump Mode Operation
8.2.1 Concentration Mode
Concentration Mode may be used to flush the module to prepare it for use. For example, some
modules must be flushed with 2 ml of water for every cm2 of its surface area. The module in the
example below has a surface area of ~0.80 m2, which means the module must be flushed with ~16L
of water.
To automate flushing the module on the TFF system while only using a Permeate Scale, the user can
simply start with 32 kg of water in the Feed Reservoir, input the value into the TFF system as 32L of
Feed Hold-up and set Feed Status Empty. Then the user must set the Conc Factor setpoint to 2X.
Once 16 kg of water has been moved from the Feed scale to the Permeate Scale, C Mode will end.
Starting Weight 32 kg
Conc Factor 1 2X Perm Wt After C1 16 kg
Feed Wt After C1
16 kg
Feed Scale* Permeate Scale
* Feed Scale is optional in this example to demonstrate how to use Feed Hold-up and Feed Fill
options.
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