REPLIGEN Spectrum KR2i

43 400-12355-000 Rev. 03
KR2i / KMPi TFF Systems
System Functionality
8.2.3 Concentration 1/Diafiltration/Concentration 2 Mode
C/D/C Mode may be used to further concentrate the process solution after Diafiltration.
Starting Weight 20 kg
Conc Factor 1 10X Perm Wt After C1 18 kg
Feed Wt After C1
2 kg
Diaf Volumes 1 7 Diaf Wt 1 14 kg
Perm Wt After D1 32 kg
Conc Factor 2 20X
Feed Wt After C2
1 kg
Feed Scale Permeate Scale
Feed Reservoir
KMPi Pump
Permeate Reservoir
Diafiltration Buffer Reservoir
Module
Diafiltration Pump
(Auxiliary Pump 1)
Feed Scale
Permeate Pump
(Auxiliary Pump 2)
Permeate Scale