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Pulmonary Function Test • Publication 014181-001 Rev 02 • www.datasci.com ©2023 Data Sciences International
Appendix B – Anesthesia
The following is a list of suggestions for anesthetizing an animal.
First Choice
For Guinea Pig, Rat, and Mouse, choose the following:
Ketamine (50 mg/kg) + Medetomidine (0.33 mg/kg) combo
Delivery : i.p. 1 mL/kg
For example:
10 mL of 1 mg/mL
Medetomidine
15 mL of 100 mg/mL Ketamine
5 mL water FI
This cocktail keeps them spontaneously breathing but allows plenty of time for the Quasi-static maneuver to
complete.
For Monkey, choose the following:
Diprivan (Propofol) 3-15
ℎ ×
The dose varies, start with 3
ℎ ×
but you might have to increase it up to as much as 15
ℎ ×
The monkey metabolizes this substance rapidly, so recovery is also relatively quick.
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