Labcyte Echo 555 - Will the Fluid Splash or Fall out

1-4 Echo Liquid Handler User Manual
1.1.2 Will the fluid splash or fall out?
The Echo liquid handler performs liquid transfer with an inverted
destination plate. Users might question whether all of the droplet remains
in the destination plate well after transfer. Will any of it splash out? Will the
repeated motions of the destination plate, or simply time passing, allow
any of the transferred liquid to fall or drain out of the destination plate
well?
Pre-loaded 1536-well destination microplates will not experience fluid loss
when they are inverted. Pre-loaded 384-well destination microplates
containing fluid with low surface tension may experience fluid loss when
inverted and should be tested. Pre-loaded 96-well destination microplates
may experience loss of fluid when inverted, depending on fluid type and
volume, and are not recommended for “wet” (pre-loaded) fluid transfers.