VNS Therapy SENTIVA M3000 Programmer - Phase 2: Duty Cycle and Additional Settings

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Phase 2: Duty Cycle
 Increase duty cycle over time and assess clinical outcome
 Adjustments to duty cycle should be less frequent (3 - 6 months)
Tachycardia Detection
ON/OFF
Heartbeat Detection*
Range (1 - 5)
Start with Sensitivity 1 and verify heartbeat detection
update. Adjust setting if necessary until accurate
detection is reached.
Threshold for AutoStim*
(% heart rate increase)
Range (20 - 70%)
Set at or below the patient’s typical heart rate increase
during a seizure
If not available, start with 20% and adjust based on
clinical benefit or tolerability
Prone Position*
Configure generator to log the occurrence of prone
position when they occur within 7.5 minutes of an
AutoStim or Magnet Mode activation
Low Heart Rate*
Range (30-60 BPM)
Configure generator to log low heart rate episodes
when they occur within 7.5 minutes of an AutoStim or
Magnet Mode activation
*Tachycardia detection must be enabled
LivaNova recommends that stimulation with Normal Mode ON time > OFF time be avoided.
Duty Cycle = (ON Time + 4 seconds) / (ON time + OFF Time), for which ON and OFF Time are
measured in seconds.
Additional Settings for SenTiva
0.2 0.3 0.5 0.8 1.1
OFF TIME (minutes)
1.8 3 5 10
7
14
21
ON TIME (seconds)
30
60
58 44 30 20 15 10 6 4 2
69 56 41 29 23 15 9 6 3
76 64 49 36 29 19 12 8 4
81 71 57 44 35 25 16 10
5
89 82 71 59 51 38 27 18 10
Not available with AutoStim Enabled
Recommended
Not recommended
Recommended progression for duty cycle