VNS Therapy SENTIVA M3000 Programmer - General Dosing Guidelines; Phase 1: Output Current Adjustment

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SENTIVA DOSING GUIDELINES
Phase 1: Output Current
Increase Output Current to therapeutic effect as tolerated by the patient
 Suggested programming settings ≥ 2 weeks post-op
 More frequent visits (1 - 2 weeks) are suggested in Phase 1
 Multiple 0.25 mA increases may be made in a single visit to reach
therapeutic range sooner; ensure patient tolerability before making
additional adjustments
 Give patient time to adapt to parameter changes before making
additional adjustments
NORMALAUTOSTIMMAGNET
Output Current
Signal Frequency
Pulse Width
Signal ON Time
Signal OFF Time
Output Current
Pulse Width
ON Time
Output Current
Pulse Width
ON Time
mA
Hz
μsec
seconds
minutes
mA
μsec
seconds
mA
μsec
seconds
0.25
20
250
30
5
0.375
250
60
0.5
500
60
0.5
20
250
30
5
0.625
250
60
0.75
500
60
0.75
20
250
30
5
0.875
250
60
1.0
500
60
1.0
20
250
30
5
1.125
250
60
1.25
500
60
1.25
20
250
30
5
1. 375
250
60
1.5
500
60
1.5
20
250
30
5
1.625
250
60
1.75
500
60
1.75
20
250
30
5
1.875
250
60
2.0
500
60
1Visit 2 3 4 5 6 7
STANDARD PROTOCOL
MAGNET MODE: Normal Mode + 0.25 mA
AUTOSTIM MODE
*
: Normal Mode + 0.125 mA
AutoStim should be comfortable for patients
Magnet Mode should be > than AutoStim Mode
NORMAL MODE: 0.25 mA steps to therapeutic eect
1,2
Dosing Notes
 Continue to optimize dose to therapeutic effect or tolerability
General Dosing Guidelines