Appendix B: Safety
Pressurized Gas Safety
Hyperion Imaging System User Guide
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the torch box are significantly above lethal levels for most single airborne cells.
However, in the event of plasma shutdown, the non-ionized portion of a sample
can enter the torch box exhaust gases.
Pressurized Gas Safety
Safe Handling of Gas Cylinders
Argon gas used with the system is normally stored in liquid argon tanks or pressurized
containers. Carefully use, store, and handle compressed gases in cylinders. Gas cylinders
can be hazardous if they are mishandled. Argon is neither explosive nor combustible.
Helium gas is supplied in the non-liquefied or liquid form in a compressed gas cylinder for
use with the Hyperion™ Imaging System.
Contact the gas supplier for a safety data sheet containing detailed information on the
potential hazards associated with the gas.
IMPORTANT If liquid argon or liquid helium is used, the gas cylinder must be fitted with an
overpressure regulator, which will vent the cylinder as necessary to prevent it from
becoming a safety hazard.
WARNING Do not use electronic pressure regulator and auto switching valves
because doing so may affect the plasma stability and may result in frequent loss of
plasma.
WARNING It is recommended to install an oxygen sensor in the room where the
operator and gas storage are located.
Sample Handling and Preparation Safety
WARNING For better control of contamination, dedicate laboratory reagents and
consumables to use with CyTOF® instruments and Maxpar® reagents only.
Radio Frequency Radiation Safety
WARNING RADIO FREQUENCY RADIATION. The system generates high levels of
RF energy, which is potentially hazardous if allowed to escape. The system is
designed to contain the RF energy within the shielded enclosures of the torch
compartment and the RF power supply. Safety interlocks prevent the system from
operating without all covers, doors, and shields in place.
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