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General| Technology | Mass Cytometry |
|---|---|
| Imaging Capability | Yes |
| Laser | Nd:YAG laser |
| Tissue Imaging Capability | Yes |
| Detection Method | Mass Spectrometry |
| Isotope Detection | Yes |
Details operator safety guidelines for the Hyperion Imaging System, classified as a Class 1 laser device.
Explains Fluidigm's specific conventions for presenting important information and safety alerts.
Covers chemical hazard indicators following the GHS system, including pictograms and signal words.
Details instrument hazard indicators including pictograms and signal words indicating severity levels.
Advises users to read and understand Safety Data Sheets (SDS) before handling chemicals.
Introduces the Hyperion Imaging System as the first IMC platform for highly multiplexed imaging.
Describes the system's technology based on laser ablation coupled with time-of-flight mass cytometry.
Provides performance specifications for the solid-state laser, including type, wavelength, and energy output.
Details system specifications including tissue thickness, sample size, scan area, and operating temperatures.
Lists the standard parts included in the Hyperion Imaging System shipment.
Specifies the recommended dimensions for slides used with the Hyperion Imaging System.
Lists available consumables and reagents for the Hyperion Imaging System and ordering information.
Provides an overview of the Hyperion Tissue Imager, including a schematic and safety warnings.
Describes the status of the sample and coupling windows and their corresponding LED indicators.
Details the Instrument Interlock LEDs on the Hyperion Tissue Imager's LED panel.
Identifies and locates other components of the Helios system, such as the AC distribution box and sampler cone.
Provides detailed step-by-step instructions for coupling the Hyperion Tissue Imager to the Helios system.
Guides users on how to start the Hyperion Imaging System and log into the CyTOF Software.
Details the procedure for unloading and loading tuning slides or sample slides into the instrument.
Explains how to turn on the laser power and confirm its status via the HTI Status Panel.
Outlines the steps for safely disconnecting the Hyperion Tissue Imager from the Helios system.
Describes how to switch the instrument's acquisition mode to Cell Suspension.
Provides instructions for cleaning various parts of the Hyperion Imaging System.
Details the procedure for cleaning the exterior surfaces of the instrument.
Provides step-by-step instructions for cleaning the Injector component.
Details the procedure for cleaning the Torch component of the system.
Provides guidance on inspecting and maintaining the coupling tube.
Describes inspection and cleaning of vacuum interface cones during preventive maintenance.
Details the procedure for replacing the load coil if it is damaged or misshapen.
Provides instructions for replacing the Injector Sealer Cap and O-ring.
Guides users on how to change the interface pump oil, including checking oil condition.
Notes that backing pump oil is changed annually by field service engineers.
Provides tips for resolving instrument initialization errors like laser not turning on.
Offers solutions for issues related to coupling tube connections and readings.
Addresses troubleshooting steps for when the laser is not firing.
Provides troubleshooting guidance for various tuning errors encountered by users.
Details common acquisition errors and their recommended solutions.
Covers miscellaneous troubleshooting issues like streaking in TIFF images and laser patterns.
Outlines decontamination procedures for biological agents using bleach solution.
Details decontamination procedures for hazardous chemicals using alcohol solutions.
Describes decontamination procedures for radioactive materials using standard decontaminants.
Provides guidance on the proper disposal of used slides, reagents, and equipment.
Recommends general safety guidelines for laboratory and manufacturing areas.
Explains the laser classification and compliance of the Hyperion Tissue Imager.
Covers warnings and guidelines for instrument safety, modifications, and biohazards.
Describes hazard symbols that may be used in the document or on system labels.
Details electrical hazards, warnings for operating without covers, and grounding requirements.
Provides safe handling guidelines for chemicals, emphasizing SDS reference and ventilation.
Discusses ventilation requirements for toxic combustion products, metal vapor, and ozone.
Covers safety precautions for handling pressurized gas cylinders like Argon and Helium.
Provides guidance on the careful use, storage, and handling of compressed gas cylinders.
Emphasizes dedicating laboratory reagents and consumables for specific instruments.
Warns about radio frequency (RF) energy hazards and the system's safety interlocks.
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