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Hyperion Imaging System User Guide
Chapter 1: Hyperion Imaging System
Introduction and Specifications
Introduction
The Hyperion™ Imaging System is the world’s first and only commercially available
metal-tagged, antibody-directed Imaging Mass Cytometry™ (IMC™) platform that allows highly
multiplexed imaging with 135 available channels. The system is designed to detect
metal-tagged antibodies bound to proteins in biological samples using standard staining
methods. The platform can simultaneously detect 4 to 37 protein markers in biological
samples including fixed tissue sections or cells deposited onto glass slides (liquid biopsies).
This allows researchers to investigate cellular subpopulations in various tissue
microenvironments. The system allows for cellular profiling in spatial proximity, enabling
subpopulation profiling and exploration of relationships of neighboring cells within the
context of the tissue structure.
Figure 1. The Hyperion Imaging System.