CAUTION
Explosion hazard if flammable liquid leaks during cleaning of
the flow path. When cleaning the flow path of ÄKTA go with a
flammable liquid like ethanol, carefully inspect the flow path, includ-
ing the waste tubing, to make sure there will be no leakage.
If hazardous chemicals are used for system or column cleaning, wash the
system or columns with a neutral solution in the last phase or step.
Tip:
Create a System CIP method
The default System CIP method comprise three phases that cleans the system with
water, 1M NaOH, and buffer from inlets Sample, C, and A respectively. The inlets used
can be changed in each phase. Follow the steps below to create a System CIP method.
ActionStep
In the Method Editor module, click the Create New Method button.1
In the New Method dialog, select System:System CIP in the Predefined
Method drop-down list. Click OK.
2
Result: A System CIP method is opened, comprising the Method Settings
phase and three System CIP phases. Each System CIP phase uses one
cleaning solution.
If desired, add additional System CIP phases to the method by dragging and
dropping them from the Phase Library.
3
ÄKTA go Operating Instructions 29360951 AC 93
7 Maintenance
7.2 Perform system Cleaning-In-Place (CIP)
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