GE Analytical Instruments ©2006 10-3 DLM 14291 Rev. A
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0 5 10 15 20 25 30 35 40
Time (sec)
[NO] (ppb)
Pressure (cm H2O)
Figure 10-1: Nasal NO Plateau.
• Have the subject inhale orally to total lung capacity and exhale orally while
maintaining a mouth pressure of 10 cm H
2
O. The NOA’s signal will slowly
increase as air is drawn through the nose, reaching a plateau within a few
seconds (Figure 10-2).
• Allow the subject to rest between replicate measurements. The ATS
recommendations do not specify how many replicates should be performed or
what repeatability should be achieved.
NOA Setup
For the nasal NO measurements, the NOA should be in the Exhalation Mode with
the Sensitivity should be set to Auto and the Com Port Interval set to 1/16 or 1/8
second. See Chapter 5 (
INSTALLATION AND SETUP: GAS-PHASE MEASUREMENTS) for
configuring the NOA. The NOA should be calibrated (Chapter 6 – CALIBRATION)
prior to measurement.
The NOAnalysis REB or Bag program can be used for data acquisition. If the Bag
program is used, the subject must watch the NOA’s front panel to maintain the
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