Test Procedures
Page 38 of 60 M1393R0 OQ/PQ Operating Instructions
4.11 Switchos Fluid Path Check
The Switchos path test is to check if the solvent selection valve close and open properly
and if the resistance of the flow path is within the specifications.
4.11.1 Performing the test
To determine if all flow paths are within the specifications:
a) Prepare the Switchos with the mobile phases listed in Section 4.12.1 and degas them
properly. Purge all four channels.
b) Disconnect the solvent inlet line from the pump head and connect the 250 µl syringe
(P/N 163241, the plunger should be removed) using an adapter (P/N 160259) as
presented in FIGURE 4-12.
FIGURE 4-12 Placing the Syringe on the Solvent Inlet Line
c) Set the flow rate to 0.00 mL/min and set the Switchos in LOCAL mode.
d) Select solvent channel A by the SSV button on the rear. The LED ‘A’ should be
illuminated.
e) Measure the flow rate from the inlet tubing for one minute.
f) Repeat steps d) and (e) for each solvent line.
g) Verify that the results meet the acceptance criteria (TABLE 2-3) and fill in the
appropriate field in the ‘Other tests’ page of the report.
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