SAFE 2010/MaxiSAFE 2010
INSTRUCTION MANUAL
Page 5 of 35
81-09-IM.doc
WARNING
The safety cabinet must not be used for Group 4 pathogens.
Attention is drawn to the risk assessment requirements of the Control of Substances Hazardous to
Health (COSHH) Regulations 1999. (UK).
WARNING
The cabinet is not suitable for HIGH-RISK biological agents.
HIGH RISK biological agents include all etiologic agents designated Class 4 by CDC, and
oncogenic viruses classed high risk by NCI. (USA).
WARNING
Never operate the Holten SAFE 2010/MaxiSAFE 2010 cabinet if the fan
compartment cover is removed.
If this cover is removed, the cabinet will give no protection of the operator or the environment and
the fan will run with openly rotating blades.
WARNING
The Holten SAFE 2010/MaxiSAFE 2010 Class II cabinet will not provide any
protection for operator or environment against harmful gases or vapours.
WARNING
Always keep your hands out of the work chamber before starting the sliding
window.
The airspeed monitoring system needs approximately 5 minutes to warm up and stabilise after the
fan has been switched on.
3. Description
3.1. Working principle
The microbiologic safety cabinet is a modified exhaust cabinet with a turbulence-free (laminar)
vertical displacement flow of clean air in the work chamber protecting the product against particle
contamination. During operation the front window is partly open and the in-going airflow prevents
the escape of particles from the inside of the work chamber thus protecting the operator and the
environment.
3.2. Air filtration
The MaxiSAFE 2010 pre-filter and the main filter and exhaust filter of SAFE 2010/MaxiSAFE 2010
are all high-efficiency HEPA filters.
3.3. Air velocity monitoring
The low turbulence vertical flow and the exhaust flow are monitored by means of air velocity
sensors. Any deviation from safe conditions will be indicated optically and acoustically.
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