Wash bottle, located in solvent tray
Reservoirs A and B
Syringe pump
Source enclosure
Probe
1.4.2 System components
The onboard system incorporates a selector valve, an infusion pump, and two sample reservoirs
mounted on the bottom, right-hand side of the instrument.
Recommendation: Use reservoir A for the calibrant solution and tuning compounds, and
reservoir B for the analyte/optimization solution.
1.4.3 System operation
The software automatically controls solvent and sample delivery during auto-tuning, auto-
calibration, and method development, via the instrument console.
See the mass spectrometer’s online Help for additional details about operation of the instrument’s
solvent delivery system.
1.5 Ion optics
The mass spectrometer’s ion optics operate as follows:
1. Samples from the LC or instrument fluidics system are introduced at atmospheric pressure
into the ionization source.
2. The ions pass through the sample cone into the vacuum system.
3. The ions pass through the transfer optics (the ion guide) to the quadrupole, where they are
filtered according to their mass-to-charge ratios.
4. The mass-separated ions pass into the T-Wave collision cell where they either undergo
collision-induced dissociation (CID) or pass to the second quadrupole.
5. The transmitted ions are detected by the photomultiplier detection system.
6. The signal is amplified, digitized, and sent to the mass spectrometry software.
January 10, 2022, 715006200 Ver. 01 (previously released as Rev. A)
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