M I N I - C U B E – U S E R M A N U A L
Rev 1.3 06/2018 42/59
Erythrocyte Sedimentation Rate (ESR), as individuals with Rheumatoid Arthritis
often have an elevated ESR.
If a diagnosis of Rheumatoid Arthritis is made, the disease activity needs to be
defined, in order to choose the treatment and evaluate its effectiveness.
For this reason the American College of Rheumatology (ACR) and European
League Against Rheumatism (EULAR) recommend the evaluation of 7 criteria to
standardize the evaluation of the response to treatment in clinical studies
(ACR/EULAR Core data Set).
These criteria are:
A. the number of painful joints
B. the number of swollen joints
C. measurement of the ESR
D. determination of functional disability based on a “Health Assessment
Questionnaire" (HAQ)
E. the degree of pain reported by the patient, expressed on a faces pain-visual
analog scale (VAS for pain)
F. the doctor’s score of the overall degree of activity of the disease, expressed
on a visual analog scale (medical VAS)
G. the patient’s rating of the overall degree of activity of the disease, expressed
on a visual analog scale (patient VAS)
Another parameter to assess RA activity, which is widely used, is the Disease
Activity Score (DAS), which uses a mathematical formula based on the following
parameters:
1. the number of painful joints
2. the number of swollen joints
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