RADIOMETER ABL800 FLEX - Page 132

5. Performance characteristics ABL800 FLEX Reference Manual
Interference tests, Continued
The substances against which the oximetry parameters (ctHb, sO
2
, FO
2
Hb,
FCOHb, FMetHb, FHHb, FHbF) and ctBil were tested for interference are given
in the table below:
Oximetry
parameters
(SAT100 blood reference test sample: ctHb=15 g/dL, sO
2
=100 %, FCOHb=0.7 %,
FMetHb=0.5 %, ctBil=0, pH=7.4. Parameter sensitivity from the influence on the
absorbance spectrum from various substances.)
Change on …
Substance Test conc.
ctHb
(g/dL)
sO
2
(%)
FO
2
Hb
(%)
FCOHb
(%)
FMetHb
(%)
FHHb
(%)
FHbF
(%)
ctBil
(
µ mol/L)
Intralipid 4 Vol %
e)
−0.5
0.1
−1.3
0.5 0.9
−0.1
11 0
4
b)
Intralipid 2 Vol %
f)
−0.4
0.1
−0.3
0.3 0.1
−0.1
11 7
2
b)
HbF
a), c)
20 %
−0.02
1.17 0.04 0.73 0.37
−1.14
0
−14
SHb 10 % 0
−1.0
0.9
−0.1
0.1
−0.9
Not tested
pH 7.1
7.9
−0.5
−0.6
−0.5
0.6
−0.2
−0.5
−0.4
1.0
0.1
0.1
0.5
−0.6
−19
13
0
−5
Cardio Green
c)
5 mg/L
−0.16
0.29 1.14 0.07
−0.93 −0.29 −5 −20
Evans Blue
c)
5 mg/L
−0.04
0.14 0.28
−0.20 −0.20
0.14
−5
5
Betacarotene in
plasma
c)
3.7 µmol/L
0.0
−0.02
0.03
−0.01 −0.04
0.02 0.1
−0.2
Patent Blue V
c)
10 mg/L
−0.16
0.39 0.86
−0.47
0.00
−0.38 −21
38
Methylene Blue
c)
30 mg/L
−0.7 −3.4
5.6
−3.0 −6.2
3.6
−37 −25
HiCN
c)
0.11
mmol/L
0.26
−1.5 −3.0 −0.5
0.5 1.5 24 47
MCHC
c), d)
newborn range
320 g/L
350 g/L
No interference
−12
17
Sedimentation rate
100 arb.
Units
≤ ± 0.5
No interference
Not
tested
Notes:
a) If function “Correction for HbF levels less than 20 %” is activated, the change is 0 for all
parameters.
b) Plasma sample.
c) Calculated value from mathematical superposition of measured pure interference spectrum
on measured reference spectrum.
d)
ctBil = 400 µmol/L.
e) Intralipid (20 % solution) at 4 Vol % gives final test level of 0.8 %.
f) Intralipid (20 % solution) at 2 Vol % gives final test level of 0.4 %.
There is no interference from fetal hemoglobin (HbF) when the analyzer applies HbF correction.
There is no interference from bilirubin (conjugated/unconjugated) up to 1000 µmol/L.
Continued on next page
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