Chapter 6 | DynaDrive S.U.B. specifications
Table 6.3. 500 L DynaDrive S.U.B. specifications.
Specification
Bioreactor geometry
Rated liquid working volume 500 L
Minimum liquid working volume 25 L
Total reactor volume (liquid & gas) 586 L
BPC chamber diameter 63 cm (25 in.)
BPC chamber shoulder height 187 cm (74 in.)
Liquid height inside tank at rated working volume 159 cm (63 in.)
Fluid geometry at working volume (height/diameter) ratio 2.7:1
Overall reactor geometry (height/diameter ratio) 3.2:1
Impeller
Impeller (quantity x blade count)
3 x 2 modified pitch blade,
1 x 2 sweep impeller
Impeller scaling (impeller diameter/tank diameter) 0.37
Impeller diameter 23 cm (9 in.)
Impeller calculated power number (N) 4
Agitation
Agitation speed range of VFD
35–120 rpm ± 1.5 rpm or 1% of setpoint,
whichever is greater
Recommended minimum during cell culture agitation (at all volumes) 50 rpm
Nominal tip speed 60 cm/s (118 ft./min.)
Motor
Agitation motor drive (type, voltage, phase), AC motor only IPM, 230 VAC, 3
AC motor power rating 400 W (0.5 hp)
Motor torque rating 5.6 Nm (76 in.-lb)
Gear reduction 15:1
Programmable VFD, remote panel interface, power fault auto restart Standard
Motor communication methods
(for external controller)
0-10 V, 4-20 mA
Motor lift power supply requirements 24 VDC, 90 psi of air
Temperature control
Jacket area: full/10% volume 0.51 m²/0.06 m² (5.5 ft.²/0.65 ft.²)
Jacket volume 13.6 L
Jacket flow rate at 3.4 bar (50 psi) 71 L/min.
Process connection 1.5 in. Sanitary tri-clamp
Recommended heating/cooling load (W) 5000 W
Approximate liquid heat-up time (5°C–37°C)—10% volume, with
ThermoFlex 10,000 TCU
1 hr
Approximate liquid heat-up time (5°C–37°C)—100% volume, with
ThermoFlex 10,000 TCU
3 hr
RTD or thermocouple: 3.18 mm (1/8 in.) OD,
15.24 cm (6 in.) length
RTD: Pt-100 (standard)
Thermo Scientific 66DynaDrive S.U.B. Service Guide
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