1260 Infinity Binary LC - System User Guide 11
The Agilent 1260 Infinity Binary LC - Product Description
1
System Components
1260 Infinity Binary Pump (G1312B)
The binary pump comprises two identical pumps integrated into one 
housing. Binary gradients are created by high- pressure mixing. Pulse 
damper and mixer can be bypassed for low flowrate applications or 
whenever a minimal transient volume is desirable. Typical applications are 
high throughput methods with fast gradients on high resolution 2.1 mm 
columns. The pump is capable of delivering flow in the range of 0.1 – 
5 mL/min against up to 600 bar. A solvent selection valve (optional) 
allows to form binary mixtures (isocratic or gradient) from one of two 
solvents per channel. Active seal wash (optional) is available for use with 
concentrated buffer solutions.
Principle of operation
The binary pump is based on a two- channel, dual- piston in- series design 
which comprises all essential functions that a solvent delivery system has 
to fulfill. Metering of solvent and delivery to the high- pressure side are 
performed by two pump assemblies which can generate pressure up to 
600 bar.
Each channel comprises a pump assembly including pump drive, pump 
head, active inlet valve with replaceable cartridge, and outlet valve. The 
two channels are fed into a low- volume mixing chamber which is 
connected via a restriction capillary coil to a damping unit and a mixer. A 
pressure sensor monitors the pump pressure. A purge valve with 
integrated PTFE frit is fitted to the pump outlet for convenient priming of 
the pumping system.