1260 Infinity Binary LC - System User Guide 17
The Agilent 1260 Infinity Binary LC - Product Description
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System Components
1290 Infinity Thermostatted Column Compartment (G1316C)
The Agilent 1290 Infinity Thermostatted Column Compartment (TCC) 
controls the temperature between 10 °C below ambient and up to 100 °C 
at 2.5 ml/min and 80 °C at up to 5 ml/min, respectively. The temperature 
stability specification is ±0.05 °C and the accuracy specification ±0.5 °C 
(with calibration)
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. This is achieved by a combination of conduction from 
contact with the thermostat vanes, still- air temperature in the column 
environment and most importantly by pre- heating (or cooling) the mobile 
phase by passing it through a heat exchanger before entering the column. 
There are two independent temperature zones in each TCC which can 
work together for long columns up to 300 mm length or work at different 
temperatures for short columns of 100 mm length or less.
The module comes with a 1.6 µl low dispersion heat exchanger and each 
valve kit contains additional low dispersion heat exchangers for each 
column. The low dispersion heat exchangers, up to 4, can be mounted 
flexibly inside the TCC. For conventional HPLC operation, 3 µl and 6 µl 
built- in heat exchangers are also available.
Each TCC can accommodate one internal valve drive to facilitate valve 
switching applications from simple switching between two columns to 
alternating column regeneration, sample preparation or column 
back- flushing. Each valve head comes as a complete kit containing all 
required capillaries, additional low dispersion heat exchangers and other 
parts.
The switching valves have exceptional ease- of- use and flexibility when 
making connections to the valve: When pressed, the drive unit of the 
Quick Change Valve slides forward for easy access (see Figure 4 on 
page 18 left). Alternative valve heads can be interchanged by the user on 
the drive mechanism for different applications (see Figure 4 on page 18 
right). Note the RFID tag on top of the valve head.
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All specifications are valid for distilled water at ambient temperature of 25 °C, setpoint at 40 °C 
and a flow range from 0.2 to 5 ml/min.