DIAL SETTINGS FOR Y-90
The typical Atomlab Dose Calibrator dial setting for Y-90
activity in a 10 cc plastic syringe is 375. This value can be
used as a starting point for initial measurements. However,
it is recommended that the dial setting used for clinical
measurements be determined from the first dose of Zevalin
received from the radiopharmacy, as outlined below. Follow
on doses should then be compared to the radiopharmacy
doses for constancy.
A sampling of Atomlab Dose Calibrators has been tested
with a NIST traceable Y-90 activity in a 10 cc plastic syringe
geometry with volumes ranging from three to nine cc. A Dial
setting range for Y-90 was determined to be 363 to 394 for
an accurate activity measurement. The average volume
dependence for this sampling of Atomlab Dose Calibrators
was determined to be 0.13%/cc, using three, four, five, six,
seven, eight and nine cc in the 10 cc plastic syringe.
Therefore, the volume dependence is negligible and the
same dial setting can be used for all volumes as distributed
by IDEC for Y-90 Zevalin.
The Y-90 recipient, using an Atomlab Dose Calibrator,
should determine the correct dial value from the first Y-90
dose that they receive from a commercial radiopharmacy.
This is determined by selecting the OTHER key and adjust-
ing the dial setting until the displayed activity agrees with
the decay corrected Y-90 syringe activity as stated by the
commercial radiopharmacy. If the adjusted dial setting falls
within the range of 363 to 394, then use that dial setting.
If it falls outside the range, then verify that:
a) there is a well liner in place
b) a hook style dipper is used
c) the annual accuracy and daily constancy tests
results are acceptable
ATOMLAB Dose Calibrator Operation Manual Appendix E
Biodex Medical Systems E-9 Release 2.0
To Next Page
Loading...
