GE Analytical Instruments ©2006 DLM 14291 Rev. A
ix
7.
ON-LINE EXHALED NITRIC OXIDE .......................................................................................................7-1
ASSEMBLY OF THE ACCURATE NO BREATH KIT.................................................................................................... 7-2
CONNECTION OF THERMAL MASS FLOWMETER..................................................................................................... 7-3
CONNECTION OF GAS SAMPLING AND PRESSURE TUBING ...................................................................................... 7-3
INSPIRATORY GAS CONNECTIONS........................................................................................................................ 7-4
Inspiratory Gas Filter............................................................................................................................ 7-4
NOA SETUP..................................................................................................................................................... 7-4
PERFORMING THE MANEUVER............................................................................................................................. 7-5
SELECTION OF NO PLATEAU.............................................................................................................................. 7-6
FLOW/PRESSURE CHARACTERISTICS OF ACCURATE NO RESTRICTORS ................................................................... 7-8
MODELS OF NITRIC OXIDE PRODUCTION IN THE AIRWAYS ..................................................................................... 7-8
CLEANING THE ACCURATE NO BREATH KIT AND FLOWMETER............................................................................... 7-9
Disassemble the Valve........................................................................................................................... 7-9
Prewash the Components................................................................................................................... 7-10
Sterilization.......................................................................................................................................... 7-10
Rinsing.................................................................................................................................................... 7-10
Drying..................................................................................................................................................... 7-10
CHECKING THE INSPIRATORY GAS FILTER.......................................................................................................... 7-11
8. OFF-LINE EXHALED NITRIC OXIDE (BAG SAMPLING) ...................................................................... 8-1
ASSEMBLY OF VITAL CAPACITY BAG COLLECTION KIT........................................................................................... 8-1
ASSEMBLY OF DEADSPACE DISCARD BAG COLLECTION KIT .................................................................................... 8-2
CLEANING THE BAGS ......................................................................................................................................... 8-5
COLLECTING THE SAMPLES – VITAL CAPACITY BAG KIT........................................................................................ 8-6
Connecting the bag to the filler......................................................................................................... 8-7
Instructing the Subject and Collecting the Samples ....................................................................... 8-7
Disconnecting the bag from the filler and sealing the bag........................................................... 8-8
COLLECTING THE SAMPLES – DEADSPACE DISCARD BAG KIT.................................................................................. 8-9
Connecting the bag to the filler......................................................................................................... 8-9
Instructing the Subject and Collecting the Samples ..................................................................... 8-10
Disconnecting the bag from the filler and sealing the bag......................................................... 8-11
ANALYZING THE SAMPLES ................................................................................................................................ 8-11
Analysis Setup....................................................................................................................................... 8-11
NOA SETUP................................................................................................................................................... 8-11
CLEANING THE BAG KITS ................................................................................................................................. 8-13
Vital Capacity Bag Kit......................................................................................................................... 8-13
Deadspace Discard Bag Kit ................................................................................................................. 8-14
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