NOVA BIOMEDICAL BIOPROFILE FLEX2 - ESM Sample Cup

2-2
BioProfile FLEX2 ESM Instructions for Use Manual
The ESM is installed using an accessory pack which is congured for either ambr® 15 or
ambr® 250 integration. In either case, the accessory pack contains the following components
necessary for FLEX2 + ambr® integration:
○ An ESM Reagent Cartridge that contains:
• System Fluid Solution
• Internal Waste Collection Pouch
• Deproteinizing Solution
• Performance Check Solution
○ A power cable for separate power supply to the ESM
○ A serial cable for communication between the ESM and FLEX2
○ An AD/VALVE cable for control of ow components
○ A Connectivity Kit for communication between the Bridge computer and ambr®
computer (See Section 3.3 for more information)
○ A sample cup for sample delivery from ambr®
2.3 ESM Sample Cup
While the reagent cartridge and required communication and power cables are shared
between the ESM15 and ESM250, the key difference between the two accessory packs
is the ESM sample cup. The acrylic sample cup is provided by Nova and mounted by
Sartorius on the ambr® deck. It serves as the transfer point where the ambr® robot arm
deposits a cell culture sample for delivery to the FLEX2. There are two different sample
cups—one that is suitable for both ambr® 15 and ambr® 250 integration (PN 59975,
Fig. 2.3A), and one that is designed for the ambr® 15 + Analysis Module (PN 60094,
Fig. 2.3B). The ESM15 accessory pack includes both cups to accommodate either
conguration (i.e. ambr® 15 with or without Analysis Module); whereas the ESM250
accessory pack includes only PN 59975, which is suitable for integration with the ambr®
250 with or without an Analysis Module.
A B
Figure 2.3 ESM Sample Cup for A) ambr® 15/250, PN 59975 B) ambr® 15 + Analysis Module, PN 60094