4 Maintenance Procedures
150 January 11, 2016, 715004599 Rev. B
Replacing the ESI probe capillary
Replace the stainless steel ESI probe capillary if it becomes irreversibly blocked, or if it
becomes contaminated or damaged.
Required materials
• Chemical-resistant, powder-free gloves
• Combined 2.5-mm Allen wrench and cone extraction tool
•7-mm wrench
•8-mm wrench
• 10-mm wrench
• Needle-nose pliers
•LC pump
• HPLC-grade (or better) 1:1 acetonitrile/water
• New capillary
• Ferrule
• Seal PTFE liner tubing
• Conductive sleeve
• Red PEEK tubing
• New nickel gasket
• PEEK tube cutter or sharp knife
• Safety goggles
Warning: To avoid personal contamination with biohazards or toxic
materials, and to avoid spreading contamination to uncontaminated surfaces,
wear clean, chemical-resistant, powder-free gloves when working with the
probe and source components.
Warning: To avoid burn injuries, take great care while performing this
procedure; the probe and source can be hot.
Warning: To avoid puncture wounds, handle the probe with care; the ESI
probe tip is sharp.