1260 Infinity Binary LC - System User Guide 117
Appendix
6
Setting Up a Method using Edit Entire Method
• Advanced - High Throughput
• Automatic delay volume reduction (ADVR) switches the injection valve 
from mainpass to bypass after the injection has taken place and a 
volume defined by the sample flush out factor has swept through the 
injector. This reduces the delay volume of the system by about 70 µl 
and allows the gradient changes to reach the column sooner.
• Enable overlapped injection also switches the injection valve from 
mainpass to bypass after the injection has taken place either after 
the sample has flushed out of the injector or at some specified later 
time in the run. The injector will then aspirate the next sample in 
readiness for the next injection thus reducing the overall cycle time 
and increasing the sample throughput.
• Injection Valve Cleaning
• Injector Cleaning allows the injection system to be flushed with solvent.
• Injection Valve Cleaning allows the valve to be switched at setpoints 
during the run to minimize carryover when problem compounds are 
injected.